Automated reporting of cervical biopsies using artificial intelligence

Mahnaz Mohammadi*, Christina Fell, David Morrison, Sheeba Syed, Prakash Konanahalli, Sarah Bell, Gareth Bryson, Ognjen Arandjelović, David J. Harrison, David Harris-Birtill

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review


When detected at an early stage, the 5-year survival rate for people with invasive cervical cancer is 92%. Being aware of signs and symptoms of cervical cancer and early detection greatly improve the chances of successful treatment. We have developed an Artificial Intelligence (AI) algorithm, trained and evaluated on cervical biopsies for automated reporting of digital diagnostics. The aim is to increase overall efficiency of pathological diagnosis and to have the performance tuned to high sensitivity for malignant cases. Having a tool for triage/identifying cancer and high grade lesions may potentially reduce reporting time by identifying areas of interest in a slide for the pathologist and therefore improving efficiency. We trained and validated our algorithm on 1738 cervical WSIs with one WSI per patient. On the independent test set of 811 WSIs, we achieved 93.4% malignant sensitivity for classifying slides. Recognising a WSI, with our algorithm, takes approximately 1.5 minutes on the NVIDIA Tesla V100 GPU. Whole slide images of different formats (TIFF, iSyntax, and CZI) can be processed using this code, and it is easily extendable to other formats.
Original languageEnglish
Article numbere0000381
JournalPLOS Digital Health
Issue number4
Publication statusPublished - 22 Apr 2024


Dive into the research topics of 'Automated reporting of cervical biopsies using artificial intelligence'. Together they form a unique fingerprint.

Cite this