[Au]/[Pd] Multicatalytic Processes: Direct One-Pot Access to Benzo[c]chromenes and Benzo[b]furans

A new synthetic protocol that combines the advantages
offered by eco-friendly solvent-free reactions
and sequential transformations is reported. This strategy
offers straightforward access to benzo[c]chromenes and
benzo[b]furans from commercially available starting materials.
This two-step, one-pot strategy consists of an Au-catalyzed
hydrophenoxylation process followed by Pd-catalyzed
CH activation or Mizoroki–Heck reactions. The selectivity
of the process towards CH activation or Mizoroki–
Heck reaction can be easily tuned.