Abstract
A new synthetic protocol that combines the advantages
offered by eco-friendly solvent-free reactions
and sequential transformations is reported. This strategy
offers straightforward access to benzo[c]chromenes and
benzo[b]furans from commercially available starting materials.
This two-step, one-pot strategy consists of an Au-catalyzed
hydrophenoxylation process followed by Pd-catalyzed
CH activation or Mizoroki–Heck reactions. The selectivity
of the process towards CH activation or Mizoroki–
Heck reaction can be easily tuned.
offered by eco-friendly solvent-free reactions
and sequential transformations is reported. This strategy
offers straightforward access to benzo[c]chromenes and
benzo[b]furans from commercially available starting materials.
This two-step, one-pot strategy consists of an Au-catalyzed
hydrophenoxylation process followed by Pd-catalyzed
CH activation or Mizoroki–Heck reactions. The selectivity
of the process towards CH activation or Mizoroki–
Heck reaction can be easily tuned.
| Original language | English |
|---|---|
| Pages (from-to) | 13507 – 13510 |
| Number of pages | 4 |
| Journal | Chemistry - A European Journal |
| Volume | 20 |
| Early online date | 28 Aug 2014 |
| DOIs | |
| Publication status | Published - 2014 |