Au/Ag-Cocatalyzed Aldoximes to Amides Rearrangement under Solvent- and Acid-Free Conditions

Ruben S. Ramon, Johann Bosson, Silvia Diez-Gonzalez, Nicolas Marion, Steven Patrick Nolan

Research output: Contribution to journalArticlepeer-review

128 Citations (Scopus)

Abstract

The gold/silver-cocatalyzed conversion of aldoximes into primary amides is reported. The reaction, which proceeds under neat and acid-free conditions, allows for the conversion of a range of aldoximes, and is a rare example of cooperative catalysis involving well-defined gold species.

Original languageEnglish
Pages (from-to)1197-1202
Number of pages6
JournalThe Journal of Organic Chemistry
Volume75
Issue number4
DOIs
Publication statusPublished - 19 Feb 2010

Keywords

  • N-HETEROCYCLIC CARBENES
  • ONE-POT
  • BECKMANN REARRANGEMENT
  • ORGANIC TRANSFORMATIONS
  • CATALYZED CONVERSION
  • HYDROXIDE CATALYST
  • HIGHLY EFFICIENT
  • GOLD CATALYSIS
  • NITRILES
  • DEHYDRATION

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