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Asymmetric synthesis of the epoxide portion of the azinomycins

  • H J Bryant
  • , C Y Dardonville
  • , T J Hodgkinson
  • , M Shipman
  • , A M Z Slawin

Research output: Contribution to journalArticlepeer-review

Abstract

A short synthesis of the epoxide fragment of the azinomycins is described. The desired (2S,3S)-stereochemistry was established using an asymmetric dihydroxylation reaction.

Original languageEnglish
Pages (from-to)973
Number of pages3
JournalSynlett
Issue number10
Publication statusPublished - Oct 1996

Keywords

  • azinomycins
  • asymmetric dihydroxylation
  • STEREOSELECTIVE SYNTHESIS
  • ANTITUMOR ANTIBIOTICS
  • CONVENIENT SYNTHESIS
  • CARZINOPHILIN
  • FRAGMENT
  • STEREOCHEMISTRY
  • CYTOTOXICITY

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