Asymmetric synthesis of the epoxide portion of the azinomycins

H J  Bryant; C Y  Dardonville; T J  Hodgkinson; M  Shipman; A M Z  Slawin

Asymmetric synthesis of the epoxide portion of the azinomycins

H J Bryant, C Y Dardonville, T J Hodgkinson, M Shipman, A M Z Slawin

Research output: Contribution to journal › Article › peer-review

Abstract

A short synthesis of the epoxide fragment of the azinomycins is described. The desired (2S,3S)-stereochemistry was established using an asymmetric dihydroxylation reaction.

Original language	English
Pages (from-to)	973
Number of pages	3
Journal	Synlett
Issue number	10
Publication status	Published - Oct 1996

Keywords

azinomycins
asymmetric dihydroxylation
STEREOSELECTIVE SYNTHESIS
ANTITUMOR ANTIBIOTICS
CONVENIENT SYNTHESIS
CARZINOPHILIN
FRAGMENT
STEREOCHEMISTRY
CYTOTOXICITY

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@article{97395433b5064f1c8ed4a8639192fef0,

title = "Asymmetric synthesis of the epoxide portion of the azinomycins",

abstract = "A short synthesis of the epoxide fragment of the azinomycins is described. The desired (2S,3S)-stereochemistry was established using an asymmetric dihydroxylation reaction.",

keywords = "azinomycins, asymmetric dihydroxylation, STEREOSELECTIVE SYNTHESIS, ANTITUMOR ANTIBIOTICS, CONVENIENT SYNTHESIS, CARZINOPHILIN, FRAGMENT, STEREOCHEMISTRY, CYTOTOXICITY",

author = "Bryant, {H J} and Dardonville, {C Y} and Hodgkinson, {T J} and M Shipman and Slawin, {A M Z}",

year = "1996",

month = oct,

language = "English",

pages = "973",

journal = "Synlett",

issn = "0936-5214",

publisher = "Georg Thieme Verlag",

number = "10",

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TY - JOUR

T1 - Asymmetric synthesis of the epoxide portion of the azinomycins

AU - Bryant, H J

AU - Dardonville, C Y

AU - Hodgkinson, T J

AU - Shipman, M

AU - Slawin, A M Z

PY - 1996/10

Y1 - 1996/10

N2 - A short synthesis of the epoxide fragment of the azinomycins is described. The desired (2S,3S)-stereochemistry was established using an asymmetric dihydroxylation reaction.

AB - A short synthesis of the epoxide fragment of the azinomycins is described. The desired (2S,3S)-stereochemistry was established using an asymmetric dihydroxylation reaction.

KW - azinomycins

KW - asymmetric dihydroxylation

KW - STEREOSELECTIVE SYNTHESIS

KW - ANTITUMOR ANTIBIOTICS

KW - CONVENIENT SYNTHESIS

KW - CARZINOPHILIN

KW - FRAGMENT

KW - STEREOCHEMISTRY

KW - CYTOTOXICITY

M3 - Article

SN - 0936-5214

SP - 973

JO - Synlett

JF - Synlett

IS - 10

ER -

Asymmetric synthesis of the epoxide portion of the azinomycins

Abstract

Keywords

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