Asymmetric synthesis of ²-amino acid scaffolds

Steven D. Bull*, Stephen G. Davies, Andrew D. Smith

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

28 Citations (Scopus)


Addition of two or three equivalents of lithium (S)-N-benzyl-N-α-methylbenzylamide to conjugate acceptors containing two or three α,β-unsaturated ester fragments respectively and subsequent hydrogenolytic deprotection afford homochiral bis- or tris-β-amino esters containing two or three new stereogenic centres in high de and ee.

Original languageEnglish
Pages (from-to)2931-2938
Number of pages8
JournalJournal of the Chemical Society. Perkin Transactions 1
Issue number22
Publication statusPublished - 29 Oct 2001


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