Asymmetric synthesis of (1R,2S,3R)-γ-methyl-cis-pentacin by a kinetic resolution protocol

Simon Bailey; Stephen G. Davies; Andrew D. Smith; Jonathan M. Withey

doi:10.1039/b209728c

Asymmetric synthesis of (1R,2S,3R)-γ-methyl-cis-pentacin by a kinetic resolution protocol

Simon Bailey, Stephen G. Davies^*, Andrew D. Smith, Jonathan M. Withey

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

30 Citations (Scopus)

Abstract

The asymmetric synthesis of (1R,2S,3R)-3-methyl-2-aminocyclopentane carboxylic acid has been achieved via kinetic resolution of racemic tert-butyl 3-methyl-cyclopentene-1-carboxylate with homochiral lithium (S)-N-benzyl-N-α-methylbenzylamide.

Original language	English
Pages (from-to)	2910-2911
Number of pages	2
Journal	Chemical Communications
Volume	2
Issue number	23
DOIs	https://doi.org/10.1039/b209728c
Publication status	Published - 1 Jan 2002

Access to Document

10.1039/b209728c

Cite this

@article{f1ad0fcb7d65461a9a46431f09f63d47,

title = "Asymmetric synthesis of (1R,2S,3R)-γ-methyl-cis-pentacin by a kinetic resolution protocol",

abstract = "The asymmetric synthesis of (1R,2S,3R)-3-methyl-2-aminocyclopentane carboxylic acid has been achieved via kinetic resolution of racemic tert-butyl 3-methyl-cyclopentene-1-carboxylate with homochiral lithium (S)-N-benzyl-N-α-methylbenzylamide.",

author = "Simon Bailey and Davies, {Stephen G.} and Smith, {Andrew D.} and Withey, {Jonathan M.}",

year = "2002",

month = jan,

day = "1",

doi = "10.1039/b209728c",

language = "English",

volume = "2",

pages = "2910--2911",

journal = "Chemical Communications",

issn = "1359-7345",

publisher = "Royal Society of Chemistry",

number = "23",

}

TY - JOUR

T1 - Asymmetric synthesis of (1R,2S,3R)-γ-methyl-cis-pentacin by a kinetic resolution protocol

AU - Bailey, Simon

AU - Davies, Stephen G.

AU - Smith, Andrew D.

AU - Withey, Jonathan M.

PY - 2002/1/1

Y1 - 2002/1/1

N2 - The asymmetric synthesis of (1R,2S,3R)-3-methyl-2-aminocyclopentane carboxylic acid has been achieved via kinetic resolution of racemic tert-butyl 3-methyl-cyclopentene-1-carboxylate with homochiral lithium (S)-N-benzyl-N-α-methylbenzylamide.

AB - The asymmetric synthesis of (1R,2S,3R)-3-methyl-2-aminocyclopentane carboxylic acid has been achieved via kinetic resolution of racemic tert-butyl 3-methyl-cyclopentene-1-carboxylate with homochiral lithium (S)-N-benzyl-N-α-methylbenzylamide.

UR - http://www.scopus.com/inward/record.url?scp=0036435540&partnerID=8YFLogxK

U2 - 10.1039/b209728c

DO - 10.1039/b209728c

M3 - Article

AN - SCOPUS:0036435540

SN - 1359-7345

VL - 2

SP - 2910

EP - 2911

JO - Chemical Communications

JF - Chemical Communications

IS - 23

ER -

Asymmetric synthesis of (1R,2S,3R)-γ-methyl-cis-pentacin by a kinetic resolution protocol

Abstract

Access to Document

Other files and links

Fingerprint

Cite this