Asymmetric Pericyclic Cascade Approach to Spirocyclic Oxindoles

Edward Richmond, Nicolas Duguet, Alexandra M. Z. Slawin, Tomas Lebl, Andrew D. Smith

Research output: Contribution to journalArticlepeer-review

45 Citations (Scopus)

Abstract

The reaction of chiral N-arylnitrones with carbocyclic alkylarylketenes generates spirocyclic oxindoles in good yields and with excellent levels of enantioselectivity (90-99% ee) via a pericyclic cascade process.

Original languageEnglish
Pages (from-to)2762-2765
Number of pages4
JournalOrganic Letters
Volume14
Issue number11
DOIs
Publication statusPublished - 1 Jun 2012

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