A2A adenosine receptor agonists with last-step enzymatic 18F-labelling potential (fluorinase) for positron emission tomography (PET)

David O'Hagan; Nicolas Charalambous; Phillip Lowe; Sergio Dall'Angelo; Carina Schleidt; Rongfang Liu; Laura Heitman

doi:10.1002/ejoc.202501125

A_2A adenosine receptor agonists with last-step enzymatic ¹⁸F-labelling potential (fluorinase) for positron emission tomography (PET)

David O'Hagan^*, Nicolas Charalambous, Phillip Lowe, Sergio Dall'Angelo, Carina Schleidt, Rongfang Liu, Laura Heitman

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Original language	English
Journal	European Journal of Organic Chemistry
Volume	Accepted/in press
DOIs	https://doi.org/10.1002/ejoc.202501125
Publication status	Published - 2 Dec 2025

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10.1002/ejoc.202501125Licence: CC BY

Exploring interactions of polar: Exploring interactions of polar fluoraliphatic motifs with biomolecules
O'Hagan, D. (PI)
EPSRC
1/12/23 → 30/11/26
Project: Standard

Cite this

@article{21e96ee4e6f64d0981cfcaa815394f85,

title = "A2A adenosine receptor agonists with last-step enzymatic 18F-labelling potential (fluorinase) for positron emission tomography (PET)",

author = "David O'Hagan and Nicolas Charalambous and Phillip Lowe and Sergio Dall'Angelo and Carina Schleidt and Rongfang Liu and Laura Heitman",

note = "Funding: EPSRC (grant number EP/X038904/1).",

year = "2025",

month = dec,

day = "2",

doi = "10.1002/ejoc.202501125",

language = "English",

volume = "Accepted/in press",

journal = "European Journal of Organic Chemistry",

issn = "1434-193X",

publisher = "Wiley-VCH, Weinheim",

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TY - JOUR

T1 - A2A adenosine receptor agonists with last-step enzymatic 18F-labelling potential (fluorinase) for positron emission tomography (PET)

AU - O'Hagan, David

AU - Charalambous, Nicolas

AU - Lowe, Phillip

AU - Dall'Angelo, Sergio

AU - Schleidt, Carina

AU - Liu, Rongfang

AU - Heitman, Laura

N1 - Funding: EPSRC (grant number EP/X038904/1).

PY - 2025/12/2

Y1 - 2025/12/2

U2 - 10.1002/ejoc.202501125

DO - 10.1002/ejoc.202501125

M3 - Article

SN - 1434-193X

VL - Accepted/in press

JO - European Journal of Organic Chemistry

JF - European Journal of Organic Chemistry

ER -

A2A adenosine receptor agonists with last-step enzymatic 18F-labelling potential (fluorinase) for positron emission tomography (PET)

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Projects

Exploring interactions of polar: Exploring interactions of polar fluoraliphatic motifs with biomolecules

Cite this

A_2A adenosine receptor agonists with last-step enzymatic ¹⁸F-labelling potential (fluorinase) for positron emission tomography (PET)