Assessing dimerisation degree and cooperativity in a biomimetic small-molecule model by pulsed EPR

Katrin Ackermann; Angeliki Giannoulis; David Bradford Cordes; Alexandra Martha Zoya Slawin; Bela Ernest Bode

doi:10.1039/C4CC08656B

Assessing dimerisation degree and cooperativity in a biomimetic small-molecule model by pulsed EPR

Katrin Ackermann, Angeliki Giannoulis, David Bradford Cordes, Alexandra Martha Zoya Slawin, Bela Ernest Bode

Research output: Contribution to journal › Article › peer-review

Abstract

Pulsed electron paramagnetic resonance (EPR) spectroscopy is gaining increasing importance as a complementary biophysical technique in structural biology. Here, we describe the synthesis, optimisation, and EPR titration studies of a spin-labelled terpyridine Zn(II) complex serving as a small-molecule model system for tuneable dimerisation.

Original language	English
Pages (from-to)	5257-5260
Number of pages	4
Journal	Chemical Communications
Volume	51
Issue number	25
Early online date	8 Jan 2015
DOIs	https://doi.org/10.1039/C4CC08656B
Publication status	Published - 28 Mar 2015

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10.1039/C4CC08656BLicence: CC BY

Bode_2015_ChemComm_Assessing_CC
© 2015 The Authors. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (http://creativecommons.org/licenses/by/3.0/)
Final published version, 1.59 MBLicence: CC BY

Cite this

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title = "Assessing dimerisation degree and cooperativity in a biomimetic small-molecule model by pulsed EPR",

abstract = "Pulsed electron paramagnetic resonance (EPR) spectroscopy is gaining increasing importance as a complementary biophysical technique in structural biology. Here, we describe the synthesis, optimisation, and EPR titration studies of a spin-labelled terpyridine Zn(II) complex serving as a small-molecule model system for tuneable dimerisation.",

author = "Katrin Ackermann and Angeliki Giannoulis and Cordes, {David Bradford} and Slawin, {Alexandra Martha Zoya} and Bode, {Bela Ernest}",

note = "AG acknowledges a postgraduate fellowship by the EPSRC funded doctoral training centre {\textquoteleft}integrated magnetic resonance{\textquoteright}. BEB is grateful for an EaStCHEM Hirst Academic Fellowship by the School of Chemistry, St Andrews, and funding from the People Programme (Marie Curie Actions) of the European Union{\textquoteright}s Seventh Framework Programme (REA 334496).",

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doi = "10.1039/C4CC08656B",

language = "English",

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T1 - Assessing dimerisation degree and cooperativity in a biomimetic small-molecule model by pulsed EPR

AU - Ackermann, Katrin

AU - Giannoulis, Angeliki

AU - Cordes, David Bradford

AU - Slawin, Alexandra Martha Zoya

AU - Bode, Bela Ernest

N1 - AG acknowledges a postgraduate fellowship by the EPSRC funded doctoral training centre ‘integrated magnetic resonance’. BEB is grateful for an EaStCHEM Hirst Academic Fellowship by the School of Chemistry, St Andrews, and funding from the People Programme (Marie Curie Actions) of the European Union’s Seventh Framework Programme (REA 334496).

PY - 2015/3/28

Y1 - 2015/3/28

N2 - Pulsed electron paramagnetic resonance (EPR) spectroscopy is gaining increasing importance as a complementary biophysical technique in structural biology. Here, we describe the synthesis, optimisation, and EPR titration studies of a spin-labelled terpyridine Zn(II) complex serving as a small-molecule model system for tuneable dimerisation.

AB - Pulsed electron paramagnetic resonance (EPR) spectroscopy is gaining increasing importance as a complementary biophysical technique in structural biology. Here, we describe the synthesis, optimisation, and EPR titration studies of a spin-labelled terpyridine Zn(II) complex serving as a small-molecule model system for tuneable dimerisation.

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DO - 10.1039/C4CC08656B

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SP - 5257

EP - 5260

JO - Chemical Communications

JF - Chemical Communications

IS - 25

ER -

Assessing dimerisation degree and cooperativity in a biomimetic small-molecule model by pulsed EPR

Abstract

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