Aryl sulfones: a new class of gamma-secretase inhibitors

M Teall, P Oakley, T Harrison, D Shaw, E Kay, J Elliott, U Gerhard, J L Castro, M Shearman, R G Ball, N N Tsou

Research output: Contribution to journalArticlepeer-review

69 Citations (Scopus)

Abstract

The development of a novel series of 4-aryl, 4-phenylsulfonyl cyclohexananone-derived gamma-secretase inhibitors for the potential treatment of Alzheimer's disease is described. (c) 2004 Elsevier Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)2685-2688
Number of pages4
JournalBioorganic and Medicinal Chemistry Letters
Volume15
Issue number10
DOIs
Publication statusPublished - 16 May 2005

Keywords

  • ALZHEIMERS-DISEASE

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