Aquaporin molecular characterization in the sea bass (Dicentrarchus labrax): The effect of salinity on AQP1 and AQP3 expression

I Giffard-Mena, V Boulo, F Aujoulat, H Fowden, R Castille, G Charmantier, Gordon Cramb

Research output: Contribution to journalArticlepeer-review

72 Citations (Scopus)

Abstract

Euryhaline fish possess the ability to compensate for environmental salinity changes through hydro-mineral regulation. A number of proteins have been studied in order to understand water and ion exchanges, known as fish osmoregulation. Sea-bass (Dicentrarchus labrax) cDNA sequences encoding a homologue of mammalian aquaporin (termed AQP1) and a homologue of mammalian aquaglyceroporin (termed AQP3) have been isolated and sequenced. The aquaporin amino acid sequences share respectively more than 60% and 65% identity with other known aquaporins. We have shown that salinity influences aquaporin expression levels in the gill, kidney and digestive tract, the main osmoregulatory organs. AQP1 may have a major osmoregulatory role in water transport in kidney and gut in SW-acclimated fish, whereas AQP3 could be implicated in gill water transport in FW-acclimated fish. (c) 2007 Elsevier Inc. All rights reserved.

Original languageEnglish
Pages (from-to)430-444
Number of pages15
JournalComparative Biochemistry and Physiology
Volume149A
DOIs
Publication statusPublished - Oct 2007

Keywords

  • aquaporins
  • gill
  • intestine
  • kidney
  • osmoregulation
  • salinity adaptation
  • teleost fish
  • water channel
  • EEL ANGUILLA-ANGUILLA
  • EUROPEAN EEL
  • FRESH-WATER
  • SEAWATER ACCLIMATION
  • CHLORIDE CELLS
  • CORTISOL TREATMENT
  • GILL EPITHELIUM
  • URINARY SYSTEM
  • OSMOREGULATION
  • PROTEIN

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