Ancient origin of the Hox gene cluster.

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161 Citations (Scopus)

Abstract

The Hox gene cluster has a crucial function in body patterning during animal development. How and when this gene cluster originated is being clarified by recent data from Cnidaria, a basal animal phylum. The characterization of Hox-like genes from Hydra, sea anemones and jellyfish has revealed that a Hox gene cluster is extremely ancient, having originated even before the divergence of these basal animals.

Original languageEnglish
Pages (from-to)33-38
Number of pages6
JournalNature Reviews Genetics
Volume2
Issue number1
DOIs
Publication statusPublished - Jan 2001

Keywords

  • HOMEOBOX-CONTAINING GENES
  • CLASS-LEVEL RELATIONSHIPS
  • EVOLUTIONARY IMPLICATIONS
  • PHYLUM CNIDARIA
  • SEA-ANEMONES
  • ORGANIZATION
  • DROSOPHILA
  • EXPRESSION
  • COMPLEX
  • ZOOTYPE

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