An Investigation of N-Aryl Sulfonation of 2-Azetidinone

RM Adlington, JE Baldwin, W McCoull, GJ Pritchard, CJ Schofield, Nicholas James Westwood

Research output: Other contribution

Abstract

N-Arylsulfonylation of 2-azetidinones can lead to the diastereoselective formation of oligomerization products. However, a simple increase of arylsulfonyl chloride concentration minimized oligomerization and allowed preparation of 1-arylsulfonyl-2-azetidinones in good yield.

Original languageEnglish
Publication statusPublished - 1997

Keywords

  • BETA-LACTAMS
  • INHIBITORS
  • DERIVATIVES

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