Activity of moxifloxacin against mycobacteria

S. H. Gillespie*, O. Billington

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Moxifloxacin is an 8-methoxyquinolone compound with activity against a wide range of bacteria. We tested its activity in comparison with four other quinolones and isoniazid against clinical isolates of mycobacteria. It proved to be the most active of the quinolones tested against Mycobacterium tuberculosis (MIC90 0.25 mg/L), Mycobacterium avium-intracellulare (MIC90 1.0 mg/L), Mycobacterium kansasii (MIC90 0.06 mg/L) and Mycobacterium fortuitum (MIC90 1 mg/L). These data indicate that moxifloxacin merits further study as an antimycobacterial agent.

Original languageEnglish
Pages (from-to)393-395
Number of pages3
JournalJournal of Antimicrobial Chemotherapy
Volume44
Issue number3
DOIs
Publication statusPublished - 20 Sept 1999

Fingerprint

Dive into the research topics of 'Activity of moxifloxacin against mycobacteria'. Together they form a unique fingerprint.

Cite this