A valuable upgrade to the portfolio of cycloaddition reactions

John C. Walton

doi:10.1002/anie.201602891

A valuable upgrade to the portfolio of cycloaddition reactions

Research output: Contribution to journal › Article › peer-review

Abstract

Recently Antonchick and Manna described a unique annulation that knits together three acetophenones to construct cyclopropanes. The cascade is mediated by organo-copper and free radical species and amounts to the first known [1+1+1] cyclotrimerization. It works well for ketones having electron-deficient or electron-rich substituents in their aryl rings.

Original language	English
Pages (from-to)	7034-7036
Number of pages	3
Journal	Angewandte Chemie International Edition
Volume	55
Issue number	25
Early online date	2 May 2016
DOIs	https://doi.org/10.1002/anie.201602891
Publication status	Published - 9 Jun 2016

Keywords

Carbocycles
Copper
Cyclotrimerization
Radicals
Synthetic methods

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10.1002/anie.201602891

CycloANIEtext1
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This work is made available online in accordance with the publisher’s policies. This is the author created, accepted version manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at https://dx.doi.org/10.1002/anie.201602891
Accepted author manuscript, 441 KBLicence: Unspecified

Cite this

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abstract = "Recently Antonchick and Manna described a unique annulation that knits together three acetophenones to construct cyclopropanes. The cascade is mediated by organo-copper and free radical species and amounts to the first known [1+1+1] cyclotrimerization. It works well for ketones having electron-deficient or electron-rich substituents in their aryl rings.",

keywords = "Carbocycles, Copper, Cyclotrimerization, Radicals, Synthetic methods",

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AB - Recently Antonchick and Manna described a unique annulation that knits together three acetophenones to construct cyclopropanes. The cascade is mediated by organo-copper and free radical species and amounts to the first known [1+1+1] cyclotrimerization. It works well for ketones having electron-deficient or electron-rich substituents in their aryl rings.

KW - Carbocycles

KW - Copper

KW - Cyclotrimerization

KW - Radicals

KW - Synthetic methods

UR - https://www.scopus.com/pages/publications/84973926517

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DO - 10.1002/anie.201602891

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JO - Angewandte Chemie International Edition

JF - Angewandte Chemie International Edition

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A valuable upgrade to the portfolio of cycloaddition reactions

Abstract

Keywords

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