A valuable upgrade to the portfolio of cycloaddition reactions

John C. Walton

doi:10.1002/anie.201602891

A valuable upgrade to the portfolio of cycloaddition reactions

Research output: Contribution to journal › Article › peer-review

Abstract

Recently Antonchick and Manna described a unique annulation that knits together three acetophenones to construct cyclopropanes. The cascade is mediated by organo-copper and free radical species and amounts to the first known [1+1+1] cyclotrimerization. It works well for ketones having electron-deficient or electron-rich substituents in their aryl rings.

Original language	English
Pages (from-to)	7034-7036
Number of pages	3
Journal	Angewandte Chemie International Edition
Volume	55
Issue number	25
Early online date	2 May 2016
DOIs	https://doi.org/10.1002/anie.201602891
Publication status	Published - 9 Jun 2016

Keywords

Carbocycles
Copper
Cyclotrimerization
Radicals
Synthetic methods

Access to Document

10.1002/anie.201602891

CycloANIEtext1
© 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim. This work is made available online in accordance with the publisher’s policies. This is the author created, accepted version manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at https://dx.doi.org/10.1002/anie.201602891
Accepted author manuscript, 441 KBLicence: Unspecified

Cite this

@article{e1720ea7227148f6bab43b97abda15b7,

title = "A valuable upgrade to the portfolio of cycloaddition reactions",

abstract = "Recently Antonchick and Manna described a unique annulation that knits together three acetophenones to construct cyclopropanes. The cascade is mediated by organo-copper and free radical species and amounts to the first known [1+1+1] cyclotrimerization. It works well for ketones having electron-deficient or electron-rich substituents in their aryl rings.",

keywords = "Carbocycles, Copper, Cyclotrimerization, Radicals, Synthetic methods",

author = "Walton, {John C.}",

note = "The author thanks EaStCHEM for financial support.",

year = "2016",

month = jun,

day = "9",

doi = "10.1002/anie.201602891",

language = "English",

volume = "55",

pages = "7034--7036",

journal = "Angewandte Chemie International Edition",

issn = "1521-3773",

publisher = "John Wiley & Sons, Ltd",

number = "25",

}

TY - JOUR

T1 - A valuable upgrade to the portfolio of cycloaddition reactions

AU - Walton, John C.

N1 - The author thanks EaStCHEM for financial support.

PY - 2016/6/9

Y1 - 2016/6/9

N2 - Recently Antonchick and Manna described a unique annulation that knits together three acetophenones to construct cyclopropanes. The cascade is mediated by organo-copper and free radical species and amounts to the first known [1+1+1] cyclotrimerization. It works well for ketones having electron-deficient or electron-rich substituents in their aryl rings.

AB - Recently Antonchick and Manna described a unique annulation that knits together three acetophenones to construct cyclopropanes. The cascade is mediated by organo-copper and free radical species and amounts to the first known [1+1+1] cyclotrimerization. It works well for ketones having electron-deficient or electron-rich substituents in their aryl rings.

KW - Carbocycles

KW - Copper

KW - Cyclotrimerization

KW - Radicals

KW - Synthetic methods

U2 - 10.1002/anie.201602891

DO - 10.1002/anie.201602891

M3 - Article

SN - 1521-3773

VL - 55

SP - 7034

EP - 7036

JO - Angewandte Chemie International Edition

JF - Angewandte Chemie International Edition

IS - 25

ER -

A valuable upgrade to the portfolio of cycloaddition reactions

Abstract

Keywords

Access to Document

Fingerprint

Cite this