A substrate mimic allows high-throughput assay of the FabA protein and consequently the identification of a novel inhibitor of Pseudomonas aeruginosa FabA

Lucile Moynie, Anthony G. Hope, Kara Finzel, Jason Schmidberger, Stuart Minto Leckie, Gunter Schneider, Michael D. Burkart, Andrew David Smith, David W. Gray, Jim Naismith

School of Chemistry
Biomedical Sciences Research Complex
EaSTCHEM

Research output: Contribution to journal › Article › peer-review

1 results
- Title
- Start date(ascending)

Crystal Structure of 3-hydroxydecanoyl-Acyl Carrier Protein Dehydratase (FabA) from Pseudomonas aeruginosa in complex with N-(4- Chlorobenzyl)-3-(2-furyl)-1H-1,2,4-triazol-5-amine (PDB entry 4CL6)
Moynie, L. (Creator), Hope, A. G. (Creator), Finzel, K. (Creator), Schmidberger, J. (Creator), Leckie, S. M. (Creator), Schneider, G. (Creator), Burkart, M. D. (Creator), Smith, A. D. (Creator), Gray, D. W. (Creator) & Naismith, J. H. (Creator), Protein Data Bank (PDB), 21 Jan 2015
DOI: 10.2210/pdb4CL6/pdb, https://www.rcsb.org/structure/4CL6
Dataset

A substrate mimic allows high-throughput assay of the FabA protein and consequently the identification of a novel inhibitor of Pseudomonas aeruginosa FabA

Datasets

Search results

Crystal Structure of 3-hydroxydecanoyl-Acyl Carrier Protein Dehydratase (FabA) from Pseudomonas aeruginosa in complex with N-(4- Chlorobenzyl)-3-(2-furyl)-1H-1,2,4-triazol-5-amine (PDB entry 4CL6)