A straightforward metal-free synthesis of 2-substituted thiazolines in air

Michael Trose; Faima Lazreg; Mathieu Lesieur; Catherine S.J. Cazin

doi:10.1039/c5gc00286a

A straightforward metal-free synthesis of 2-substituted thiazolines in air

Michael Trose, Faima Lazreg, Mathieu Lesieur, Catherine S.J. Cazin

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Abstract

A base-catalysed procedure for the synthesis of 2-substituted thiazolines from nitriles and cysteamine hydrochloride under solvent-free conditions is presented. This straightforward approach allows high conversion for a broad range of nitriles and an easy isolation of the desired products.

Original language	English
Pages (from-to)	3090-3092
Number of pages	3
Journal	Green Chemistry
Volume	17
Issue number	5
Early online date	9 Apr 2015
DOIs	https://doi.org/10.1039/c5gc00286a
Publication status	Published - 1 May 2015

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10.1039/c5gc00286a

195548666_C5GC00286A_Trose
Copyright 2015 the Authors. This work is made available online in accordance with the publisher’s policies. This is the author created, accepted version manuscript following peer review and may differ slightly from the final published version. The final published version of this work is available at: https://dx.doi.org/10.1039/C5GC00286A
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title = "A straightforward metal-free synthesis of 2-substituted thiazolines in air",

abstract = "A base-catalysed procedure for the synthesis of 2-substituted thiazolines from nitriles and cysteamine hydrochloride under solvent-free conditions is presented. This straightforward approach allows high conversion for a broad range of nitriles and an easy isolation of the desired products.",

author = "Michael Trose and Faima Lazreg and Mathieu Lesieur and Cazin, {Catherine S.J.}",

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AU - Trose, Michael

AU - Lazreg, Faima

AU - Lesieur, Mathieu

AU - Cazin, Catherine S.J.

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AB - A base-catalysed procedure for the synthesis of 2-substituted thiazolines from nitriles and cysteamine hydrochloride under solvent-free conditions is presented. This straightforward approach allows high conversion for a broad range of nitriles and an easy isolation of the desired products.

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A straightforward metal-free synthesis of 2-substituted thiazolines in air

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