A recognition-mediated reaction drives amplification within a dynamic library

Jan Witold Sadownik; Douglas Philp

doi:10.1039/C5OB01621E

A recognition-mediated reaction drives amplification within a dynamic library

Jan Witold Sadownik, Douglas Philp

Research output: Contribution to journal › Article › peer-review

Abstract

A single, appropriately designed, recognition event targets and transforms one of two reactive members of an exchanging pool of compounds through a recognition-mediated irreversible cycloaddition reaction, altering dramatically the final composition and kinetic behaviour of the dynamic library.

Original language	English
Pages (from-to)	10392-10401
Journal	Organic & Biomolecular Chemistry
Volume	13
Issue number	41
Early online date	25 Aug 2015
DOIs	https://doi.org/10.1039/C5OB01621E
Publication status	Published - 7 Nov 2015

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10.1039/C5OB01621E

Philp_2015_OBC_Recognition_CCBY
Copyright 2015 the Authors. This article is licensed under a Creative Commons Attribution 3.0 Unported Licence (http://creativecommons.org/licenses/by/3.0/).
Final published version, 3.34 MBLicence: CC BY

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title = "A recognition-mediated reaction drives amplification within a dynamic library",

abstract = "A single, appropriately designed, recognition event targets and transforms one of two reactive members of an exchanging pool of compounds through a recognition-mediated irreversible cycloaddition reaction, altering dramatically the final composition and kinetic behaviour of the dynamic library.",

author = "Sadownik, {Jan Witold} and Douglas Philp",

note = "The authors thank EaStCHEM (Graduate Studentship to JWS) and the University of St Andrews for financial support. ",

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A recognition-mediated reaction drives amplification within a dynamic library

Abstract

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