A polymorphism in the CYP17 gene is associated with male breast cancer

Christopher Michael Steel, IE Young, KM Kurian, C Annink, other 5

Research output: Contribution to journalArticlepeer-review

77 Citations (Scopus)

Abstract

The CYP17 gene codes for the cytochrome P450c17 alpha enzyme that is involved in the synthesis of oestrogens. This case-control study from the South East of Scotland shows that a polymorphism of the CYP17 gene is associated with an increased risk of male breast cancer.

Original languageEnglish
Pages (from-to)141-143
Number of pages3
JournalBritish Journal of Cancer
Volume81
Issue number1
Publication statusPublished - Sept 1999

Keywords

  • CYP17 polymorphism
  • male breast cancer
  • ANDROGEN RECEPTOR GENE
  • MUTATION
  • BRCA2

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