A new approach to the synthesis of non-racemic isoindolin-1-one derivatives

S M Allin, C J Northfield, M I Page, A M Z Slawin

Research output: Contribution to journalArticlepeer-review

35 Citations (Scopus)

Abstract

A new approach for the synthesis of non-racemic 3-substituted isoindolin-1-one targets has been developed through application of a tricyclic gamma-lactam substrate as an N-acyliminium ion precursor. (C) 1998 Elsevier Science Ltd. All rights reserved.

Original languageEnglish
Pages (from-to)141-142
Number of pages2
JournalTetrahedron Letters
Volume40
Issue number1
DOIs
Publication statusPublished - 1 Jan 1999

Keywords

  • amino alcohols
  • aminals
  • stereocontrol
  • transition states
  • nitrogen heterocycles

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