A new approach to the synthesis of non-racemic isoindolin-1-one derivatives

S M  Allin; C J  Northfield; M I  Page; A M Z  Slawin

doi:10.1016/S0040-4039(98)80041-5

A new approach to the synthesis of non-racemic isoindolin-1-one derivatives

S M Allin, C J Northfield, M I Page, A M Z Slawin

Research output: Contribution to journal › Article › peer-review

Abstract

A new approach for the synthesis of non-racemic 3-substituted isoindolin-1-one targets has been developed through application of a tricyclic gamma-lactam substrate as an N-acyliminium ion precursor. (C) 1998 Elsevier Science Ltd. All rights reserved.

Original language	English
Pages (from-to)	141-142
Number of pages	2
Journal	Tetrahedron Letters
Volume	40
Issue number	1
DOIs	https://doi.org/10.1016/S0040-4039(98)80041-5
Publication status	Published - 1 Jan 1999

Keywords

amino alcohols
aminals
stereocontrol
transition states
nitrogen heterocycles

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10.1016/S0040-4039(98)80041-5

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title = "A new approach to the synthesis of non-racemic isoindolin-1-one derivatives",

abstract = "A new approach for the synthesis of non-racemic 3-substituted isoindolin-1-one targets has been developed through application of a tricyclic gamma-lactam substrate as an N-acyliminium ion precursor. (C) 1998 Elsevier Science Ltd. All rights reserved.",

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AU - Slawin, A M Z

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AB - A new approach for the synthesis of non-racemic 3-substituted isoindolin-1-one targets has been developed through application of a tricyclic gamma-lactam substrate as an N-acyliminium ion precursor. (C) 1998 Elsevier Science Ltd. All rights reserved.

KW - amino alcohols

KW - aminals

KW - stereocontrol

KW - transition states

KW - nitrogen heterocycles

U2 - 10.1016/S0040-4039(98)80041-5

DO - 10.1016/S0040-4039(98)80041-5

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EP - 142

JO - Tetrahedron Letters

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A new approach to the synthesis of non-racemic isoindolin-1-one derivatives

Abstract

Keywords

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