A generic recognition-based approach to the acceleration of cycloaddition reactions

S J Howell, N Spencer, D Philp

Research output: Contribution to journalArticlepeer-review

Abstract

GRAPHICS

Dicarboxylic acids accelerate the rate of cycloaddition reactions between either an azide or a furan and a maleimide through the formation of a reactive 1:1:1 complex stabilized by four hydrogen bonds.

Original languageEnglish
Pages (from-to)273-276
Number of pages4
JournalOrganic Letters
Volume4
DOIs
Publication statusPublished - 24 Jan 2002

Keywords

  • DIELS-ALDER REACTIONS
  • INTRAMOLECULAR REACTIONS
  • ARTIFICIAL ENZYMES
  • CATALYSIS
  • EXTENSIONS
  • CHEMISTRY
  • RECEPTORS
  • MIMICS

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