A GENERAL METHODOLOGY FOR THE SYNTHESIS OF SUBSTITUTED PHENOLS FROM PYRANONE PRECURSORS

Laura J. Marshall; Karl M. Cable; Nigel P. Botting

A GENERAL METHODOLOGY FOR THE SYNTHESIS OF SUBSTITUTED PHENOLS FROM PYRANONE PRECURSORS

Laura J. Marshall
, Karl M. Cable
, Nigel P. Botting

Research output: Contribution to journal › Article › peer-review

Abstract

Phenols are an important group of organic compounds,(1) with many natural products such as polyketides, coumarins and flavonoids containing mono- or poly-phenolic moieties. The synthesis of substituted phenols from pyranone precursors is presented. A variety of pronucleophiles were used in combination with tert-butanol as solvent and potassium tert-butoxide as base, using both conventional heating methods and microwave conditions.

Original language	English
Pages (from-to)	457-459
Number of pages	3
Journal	Journal of Labelled Compounds and Radiopharmaceuticals
Volume	53
Issue number	5-6
Publication status	Published - 15 May 2010

Keywords

phenol
pyranone
maltol
chelidonic acid
pronucleophile
ACID

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title = "A GENERAL METHODOLOGY FOR THE SYNTHESIS OF SUBSTITUTED PHENOLS FROM PYRANONE PRECURSORS",

abstract = "Phenols are an important group of organic compounds,(1) with many natural products such as polyketides, coumarins and flavonoids containing mono- or poly-phenolic moieties. The synthesis of substituted phenols from pyranone precursors is presented. A variety of pronucleophiles were used in combination with tert-butanol as solvent and potassium tert-butoxide as base, using both conventional heating methods and microwave conditions.",

keywords = "phenol, pyranone, maltol, chelidonic acid, pronucleophile, ACID",

author = "Marshall, \{Laura J.\} and Cable, \{Karl M.\} and Botting, \{Nigel P.\}",

year = "2010",

month = may,

day = "15",

language = "English",

volume = "53",

pages = "457--459",

journal = "Journal of Labelled Compounds and Radiopharmaceuticals",

issn = "0362-4803",

publisher = "John Wiley \& Sons, Ltd",

number = "5-6",

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TY - JOUR

T1 - A GENERAL METHODOLOGY FOR THE SYNTHESIS OF SUBSTITUTED PHENOLS FROM PYRANONE PRECURSORS

AU - Marshall, Laura J.

AU - Cable, Karl M.

AU - Botting, Nigel P.

PY - 2010/5/15

Y1 - 2010/5/15

N2 - Phenols are an important group of organic compounds,(1) with many natural products such as polyketides, coumarins and flavonoids containing mono- or poly-phenolic moieties. The synthesis of substituted phenols from pyranone precursors is presented. A variety of pronucleophiles were used in combination with tert-butanol as solvent and potassium tert-butoxide as base, using both conventional heating methods and microwave conditions.

AB - Phenols are an important group of organic compounds,(1) with many natural products such as polyketides, coumarins and flavonoids containing mono- or poly-phenolic moieties. The synthesis of substituted phenols from pyranone precursors is presented. A variety of pronucleophiles were used in combination with tert-butanol as solvent and potassium tert-butoxide as base, using both conventional heating methods and microwave conditions.

KW - phenol

KW - pyranone

KW - maltol

KW - chelidonic acid

KW - pronucleophile

KW - ACID

UR - https://www.scopus.com/pages/publications/77955127861

M3 - Article

SN - 0362-4803

VL - 53

SP - 457

EP - 459

JO - Journal of Labelled Compounds and Radiopharmaceuticals

JF - Journal of Labelled Compounds and Radiopharmaceuticals

IS - 5-6

ER -

A GENERAL METHODOLOGY FOR THE SYNTHESIS OF SUBSTITUTED PHENOLS FROM PYRANONE PRECURSORS

Abstract

Keywords

Handle.net

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