A convenient catalyst system for microwave accelerated cross-coupling of a range of aryl boronic acids with aryl chlorides

Matthew L. Clarke, Marcia B. France, José A. Fuentes, Edward J. Milton, Geoffrey J. Roff

Research output: Contribution to journalArticlepeer-review

12 Citations (Scopus)

Abstract

A convenient microwave accelerated cross-coupling procedure between aryl chlorides with a range of boronic acids has been developed. An explanation for the low reactivity of highly fluorinated boronic acids in Suzuki coupling is provided.

Original languageEnglish
Article number18
Number of pages4
JournalBeilstein Journal of Organic Chemistry
Volume3
DOIs
Publication statusPublished - 30 May 2007

Keywords

  • II RECEPTOR ANTAGONIST
  • FREE HIYAMA REACTION
  • EFFICIENT SYNTHESIS
  • ARYLBORONIC ACIDS
  • ORGANIC-SYNTHESIS
  • ROOM-TEMPERATURE
  • SODIUM-HYDROXIDE
  • STILLE REACTION

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