(8RS)-4-Amino-6-(4-chlorophenyl)-8-(2,4-dichlorothiazol-5-yl)-8, 9-dihydro-7H-pyrimido[4,5-b][1,4]diazepine N,N-dimethylformamide monosolvate: sheets built from N-H⋯N and C-H⋯O hydrogen bonds

J. Ramírez, B. Insuasty, J. Cobo, C. Glidewell

Research output: Contribution to journalArticlepeer-review

Abstract

In the title compound, C16H11Cl3N6S·C3H7NO, the seven-membered ring adopts a conformation which is close to the twist-boat form. The molecular components are linked into sheets by a combination of two N-H⋯N hydrogen bonds and two C-H⋯O hydrogen bonds. Comparisons are made with other aminopyrimidine derivatives.

Original languageEnglish
Pages (from-to)536-540
Number of pages5
JournalActa Crystallographica Section C Structural Chemistry
Volume70
Issue number6
DOIs
Publication statusPublished - 1 Jun 2014

Keywords

  • Crystal structure
  • Biological properties
  • Pharmacological properties
  • Pyrimido[4,5-b][1,4]diazepine
  • Hydrogen bonding

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