3D Monte Carlo radiation transfer modelling of photodynamic therapy

Catherine Louise Campbell, C. Christison, C Tom A Brown, Kenny Wood, Ronan Martin Valentine, H. Moseley

Research output: Chapter in Book/Report/Conference proceedingConference contribution

3 Citations (Scopus)
2 Downloads (Pure)

Abstract

The effects of ageing and skin type on Photodynamic Therapy (PDT) for different treatment methods have been theoretically investigated. A multilayered Monte Carlo Radiation Transfer model is presented where both daylight activated PDT and conventional PDT are compared. It was found that light penetrates deeper through older skin with a lighter complexion, which translates into a deeper effective treatment depth. The effect of ageing was found to be larger for darker skin types. The investigation further strengthens the usage of daylight as a potential light source for PDT where effective treatment depths of about 2 mm can be achieved.
Original languageEnglish
Title of host publicationBiophotonics South America
EditorsChristina Kurachi, Katarina Svanberg, Bruce J. Tromberg, Vanderlei S. Bagnato
PublisherSPIE
ISBN (Print)9781628416961
DOIs
Publication statusPublished - Jun 2015
EventBiophotonics South America - Rio de Janeiro, Brazil
Duration: 23 May 2015 → …

Publication series

NameProceedings of SPIE
Volume9531
ISSN (Print)1605-7422

Conference

ConferenceBiophotonics South America
Country/TerritoryBrazil
CityRio de Janeiro
Period23/05/15 → …

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