2-(aminoaryl)alkanone O-phenyl oximes: versatile reagents for syntheses of quinazolines

Fernando Portela-Cubillo, Jackie S. Scott, John C. Walton

Research output: Contribution to journalArticlepeer-review

75 Citations (Scopus)

Abstract

Microwave irradiations of 2-(aminoaryl)alkanone O-phenyl oximes and carbonyl compounds generate iminyl radicals in company with imines; iminyl on imine ring closure yields dihydroquinazolines or quinazolines when ZnCl2 is included in the mixture.

Original languageEnglish
Pages (from-to)2935-2937
Number of pages3
JournalChemical Communications
Issue number25
DOIs
Publication statusPublished - 2008

Keywords

  • RADICAL CYCLIZATION
  • IMINYL RADICALS
  • INHIBITORS
  • ACETYLOXIMES
  • DERIVATIVES
  • PYRIDINES
  • ACETONE
  • AGENTS

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