2-Amino-4-chloro-6-[N-methyl-N-(4-methylphenyl)amino]pyrimidine: formation versus fragmentation of hydrogen-bonded chains of edge-fused R-2(2)(8) rings in 4,6-disubstituted 2-aminopyrimidines

Ricaurte Rodriguez; Manuel Nogueras; Justo Cobo; John N. Low; Christopher Glidewell

doi:10.1107/S0108270108016405

2-Amino-4-chloro-6-[N-methyl-N-(4-methylphenyl)amino]pyrimidine: formation versus fragmentation of hydrogen-bonded chains of edge-fused R-2(2)(8) rings in 4,6-disubstituted 2-aminopyrimidines

Ricaurte Rodriguez, Manuel Nogueras, Justo Cobo, John N. Low, Christopher Glidewell

School of Chemistry

Research output: Contribution to journal › Article › peer-review

Abstract

Molecules of the title compound, C12H13ClN4, are linked by two independent N-H center dot center dot center dot N hydrogen bonds into a chain of edge-fused R-2(2)(8) rings. The significance of this study lies in its attempt to rationalize the patterns of supramolecular aggregation in the title compound and in a range of analogous 4,6-disubstituted 2-aminopyrimidines.

Original language	English
Number of pages	3
Journal	Acta Crystallographica Section C-Crystal Structure Communications
Volume	64
DOIs	https://doi.org/10.1107/S0108270108016405
Publication status	Published - Jul 2008

Keywords

SUPRAMOLECULAR STRUCTURES
INTERPLAY

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10.1107/S0108270108016405

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Rodriguez, R., Nogueras, M., Cobo, J., Low, J. N., & Glidewell, C. (2008). 2-Amino-4-chloro-6-[N-methyl-N-(4-methylphenyl)amino]pyrimidine: formation versus fragmentation of hydrogen-bonded chains of edge-fused R-2(2)(8) rings in 4,6-disubstituted 2-aminopyrimidines. Acta Crystallographica Section C-Crystal Structure Communications, 64. https://doi.org/10.1107/S0108270108016405

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title = "2-Amino-4-chloro-6-[N-methyl-N-(4-methylphenyl)amino]pyrimidine: formation versus fragmentation of hydrogen-bonded chains of edge-fused R-2(2)(8) rings in 4,6-disubstituted 2-aminopyrimidines",

abstract = "Molecules of the title compound, C12H13ClN4, are linked by two independent N-H center dot center dot center dot N hydrogen bonds into a chain of edge-fused R-2(2)(8) rings. The significance of this study lies in its attempt to rationalize the patterns of supramolecular aggregation in the title compound and in a range of analogous 4,6-disubstituted 2-aminopyrimidines.",

keywords = "SUPRAMOLECULAR STRUCTURES, INTERPLAY",

author = "Ricaurte Rodriguez and Manuel Nogueras and Justo Cobo and Low, {John N.} and Christopher Glidewell",

year = "2008",

month = jul,

doi = "10.1107/S0108270108016405",

language = "English",

volume = "64",

journal = "Acta Crystallographica Section C-Crystal Structure Communications",

issn = "1600-5759",

publisher = "International Union of Crystallography",

}

Rodriguez, R, Nogueras, M, Cobo, J, Low, JN & Glidewell, C 2008, '2-Amino-4-chloro-6-[N-methyl-N-(4-methylphenyl)amino]pyrimidine: formation versus fragmentation of hydrogen-bonded chains of edge-fused R-2(2)(8) rings in 4,6-disubstituted 2-aminopyrimidines', Acta Crystallographica Section C-Crystal Structure Communications, vol. 64. https://doi.org/10.1107/S0108270108016405

2-Amino-4-chloro-6-[N-methyl-N-(4-methylphenyl)amino]pyrimidine: formation versus fragmentation of hydrogen-bonded chains of edge-fused R-2(2)(8) rings in 4,6-disubstituted 2-aminopyrimidines. / Rodriguez, Ricaurte; Nogueras, Manuel; Cobo, Justo et al.
In: Acta Crystallographica Section C-Crystal Structure Communications, Vol. 64, 07.2008.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - 2-Amino-4-chloro-6-[N-methyl-N-(4-methylphenyl)amino]pyrimidine: formation versus fragmentation of hydrogen-bonded chains of edge-fused R-2(2)(8) rings in 4,6-disubstituted 2-aminopyrimidines

AU - Rodriguez, Ricaurte

AU - Nogueras, Manuel

AU - Cobo, Justo

AU - Low, John N.

AU - Glidewell, Christopher

PY - 2008/7

Y1 - 2008/7

N2 - Molecules of the title compound, C12H13ClN4, are linked by two independent N-H center dot center dot center dot N hydrogen bonds into a chain of edge-fused R-2(2)(8) rings. The significance of this study lies in its attempt to rationalize the patterns of supramolecular aggregation in the title compound and in a range of analogous 4,6-disubstituted 2-aminopyrimidines.

AB - Molecules of the title compound, C12H13ClN4, are linked by two independent N-H center dot center dot center dot N hydrogen bonds into a chain of edge-fused R-2(2)(8) rings. The significance of this study lies in its attempt to rationalize the patterns of supramolecular aggregation in the title compound and in a range of analogous 4,6-disubstituted 2-aminopyrimidines.

KW - SUPRAMOLECULAR STRUCTURES

KW - INTERPLAY

U2 - 10.1107/S0108270108016405

DO - 10.1107/S0108270108016405

M3 - Article

SN - 1600-5759

VL - 64

JO - Acta Crystallographica Section C-Crystal Structure Communications

JF - Acta Crystallographica Section C-Crystal Structure Communications

ER -

2-Amino-4-chloro-6-[N-methyl-N-(4-methylphenyl)amino]pyrimidine: formation versus fragmentation of hydrogen-bonded chains of edge-fused R-2(2)(8) rings in 4,6-disubstituted 2-aminopyrimidines

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Keywords

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