Unravelling structure and function of the tRNA methyltransferases NSUN2 and METTL1: towards overcoming resistance to and potentiating 5-fluorouracil action

Guimaraes da Silva, Rafael (PI)

School of Biology

Project: Studentship

Acronym	Unravelling structure and function of
Status	Finished
Effective start/end date	27/09/22 → 26/09/25

Funding

Cunningham Trust: £98,626.00

Kinetic and thermodynamic characterization of human 4-oxo-L-proline reductase catalysis
Pecaver, E., Zickuhr, G. M., Machado, T. F. G., Harrison, D. J. & da Silva, R. G., 18 Feb 2025, In: Biochemistry. 64, 4, p. 860-870 11 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File

HsBDH2-NADH binding isotope effect data (dataset)
Pecaver, E. (Creator), Zickuhr, G. M. (Creator), Harrison, D. (Creator) & Guimaraes da Silva, R. (Creator), University of St Andrews, 27 Nov 2025
DOI: 10.17630/821f4347-65de-46d0-9459-e01b1261f9b0
Dataset

File