Research output per year
Research output per year
Search results
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2020
Dissecting the mechanism of (R)-3-hydroxybutyrate dehydrogenase by kinetic isotope effects, protein crystallography, and computational chemistry
G. Machado, T. F., Purg, M., McMahon, S., Read, B., Oehler, V., Åqvist, J., Gloster, T. & da Silva, R. G., 18 Dec 2020, In: ACS Catalysis. 10, 24, p. 15019–15032Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2018
Linear Eyring plots conceal a change in rate-limiting step in an enzyme reaction
Machado, T. F. G., Gloster, T. & da Silva, R. G., 11 Dec 2018, In: Biochemistry. 57, 49, p. 6757-6761Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Metabolic inhibitors of O-GlcNAc transferase (OGT) that act in vivo implicate decreased O-GlcNAc levels in leptin-mediated nutrient sensing
Liu, T.-W., Zandberg, W. F., Gloster, T. M., Deng, L., Murray, K. D., Shan, X. & Vocadlo, D. J., 19 Jun 2018, In: Angewandte Chemie International Edition. 57, 26, p. 7644-7648 5 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
New irreversible α-ʟ-iduronidase inhibitors and activity-based probes
Artola, M., Kuo, C.-L., McMahon, S. A., Oehler, V., Hansen, T., van der Lienden, M., He, X., van den Elst, H., Florea, B. I., Kermode, A. R., van der Marel, G. A., Gloster, T. M., Codée, J. D. C., Overkleeft, H. S. & Aerts, J. M. F. G., 26 Nov 2018, (E-pub ahead of print) In: Chemistry - A European Journal. Early View, 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2017
The enzymatic degradation of heparan sulfate
Griffin, L. S. & Gloster, T. M., 1 Aug 2017, In: Protein & Peptide Letters. 24, 8, p. 710-722Research output: Contribution to journal › Review article › peer-review
Open AccessFile -
2016
Mechanism of the human nucleocytoplasmic hexosaminidase D
Alteen, M. G., Oehler, V., Nemčovičová, I., Wilson, I. B. H., Vacadlo, D. J. & Gloster, T. M., 17 May 2016, In: Biochemistry. 55, 19, p. 2753-2747Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Structural snapshots for mechanism-based inactivation of a glycoside hydrolase by cyclopropyl carbasugars
Adamson, C., Pengelly, R. J., Kazem Abadi, S. S., Chakladar, S., Draper, J., Britton, R., Gloster, T. M. & Bennet, A. J., 18 Nov 2016, In: Angewandte Chemie International Edition. 55, 48, p. 14978-14982Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2014
Advances in understanding glycosyltransferases from a structural perspective
Gloster, T. M., Oct 2014, In: Current Opinion in Structural Biology. 28, p. 131-141 11 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2013
Characterization and downstream mannose phosphorylation of human recombinant α-L-iduronidase produced in Arabidopsis complex glycan-deficient (cgl) seeds
He, X., Pierce, O., Haselhorst, T., Kolarich, D., Packer, N. H., Gloster, T., Vocadlo, D. J., Qian, Y., Brooks, D. & Kermode, A. R., Dec 2013, In: Plant Biotechnology Journal. 11, 9, p. 1034–1043Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The development of selective inhibitors of NagZ: increased susceptibility of Gram-negative bacteria to β-lactams
Stubbs, K. A., Bacik, J.-P., Perley-Robertson, G. E., Whitworth, G. E., Gloster, T. M., Vocadlo, D. J. & Mark, B. L., Oct 2013, In: ChemBioChem. 14, 15, p. 1973-1981Research output: Contribution to journal › Article › peer-review
Open AccessFile -
2012
Development of inhibitors as research tools for carbohydrate-processing enzymes
Gloster, T. M., Oct 2012, In: Biochemical Society Transactions. 40, p. 913-928 16 p.Research output: Contribution to journal › Article › peer-review