Underpinning Mechanistic Studies of NHC-Organocatalysis: A Breslow Intermediate Reactivity Scale

Smith, Andrew (PI)

School of Chemistry

Project: Standard

Acronym	Underpinning Mechanistic Studies
Status	Finished
Effective start/end date	1/04/19 → 31/12/22

Funding

EPSRC: £398,307.60

8 Article

Isothiourea-catalysed enantioselective synthesis of phosphonate-functionalised β-lactones
Platt, F. M., Wang, Y., Cordes, D. B., McKay, A. P., Slawin, A. M. Z., Panchal, H. & Smith, A. D., 6 Mar 2025, (E-pub ahead of print) In: Chemical Science. Advance Articles, 9 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Quantifying Breslow intermediate reactivity in intermolecular Stetter reactions
Duan, Z., Zhu, J., Majhi, P. K., Goodfellow, A. S., O'Donoghue, A. C., Young, C. M. & Smith, A. D., 22 Aug 2025, (E-pub ahead of print) In: Chemical Science. Advance Article, 10 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
α-Phenylthioaldehydes for the effective generation of acyl azolium and azolium enolate intermediates
Ewing, P., Majhi, P., Prentice, C., Young, C. M., Van Rees, K., Arnold, P., Zysman-Colman, E. & Smith, A. D., 14 May 2024, In: Chemical Science. 24, 15, p. 9369-9375
Research output: Contribution to journal › Article › peer-review

Open Access
File

data underpinning "a-Phenylthioaldehydes for the effective generation of acyl azolium and azolium enolate intermediates"
Smith, A. D. (Creator), Majhi, P. (Creator), Zysman-Colman, E. (Creator), Prentice, C. (Creator), Ewing, P. (Creator), Young, C. M. (Creator), Van Rees, K. (Creator) & Arnold, P. (Creator), University of St Andrews, 30 Jul 2024
DOI: 10.17630/b0dfa038-03b4-4054-a2a3-72a4e1593b16
Dataset

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Kinetic and Structure-Activity Studies of the Triazolium Ion- catalyzed Intramolecular Stetter Reaction (dataset)
Smith, A. D. (Creator) & Young, C. M. (Creator), University of St Andrews, 2 Jun 2021
DOI: 10.17630/7b18dcdd-72a3-4b26-909b-25ccd31cd58c
Dataset

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Data underpinning "Rate and Equilibrium Constants for the Addition of Triazolium Salt derived N-Heterocyclic Carbenes to Heteroaromatic Aldehydes"
Smith, A. D. (Creator), Duan, Z. (Creator) & Young, C. M. (Creator), University of St Andrews, 30 Nov 2022
DOI: 10.17630/4e21c331-2fa6-440f-8636-f9ed563bda3c
Dataset

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