Project Details
| Acronym | Transport and Polymerisation INV Award |
|---|---|
| Status | Finished |
| Effective start/end date | 1/07/13 → 30/06/20 |
Funding
- The Wellcome Trust: £1,200,432.00
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Fingerprint
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Structure of WzxE the lipid III flippase for enterobacterial common antigen polysaccharide
Le Bas, A., Clarke, B. R., Teelucksingh, T., Lee, M., El Omari, K., Giltrap, A. M., McMahon, S. A., Liu, H., Beale, J. H., Mykhaylyk, V., Duman, R., Paterson, N. G., Ward, P. N., Harrison, P. J., Weckener, M., Pardon, E., Steyaert, J., Liu, H., Quigley, A. & Davis, B. G. & 3 others, , 8 Jan 2025, In: Open Biology. 15, 1, p. 1-19 19 p., 240310.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Next generation glucose-1-phosphate thymidylyltransferase (RmlA) inhibitors: an extended SAR study to direct future design
Xiao, G., Alphey, M. S., Tran, F., Pirrie, L., Milbeo, P., Zhou, Y., Bickel, J. K., Kempf, O., Kempf, K., Naismith, J. H. & Westwood, N. J., 15 Nov 2021, In: Bioorganic & Medicinal Chemistry. 50, 116477.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The complex of ferric-enterobactin with its transporter from Pseudomonas aeruginosa suggests a two-site model
Moynié, L., Milenkovic, S., Mislin, G. L. A., Gasser, V., Malloci, G., Baco, E., McCaughan, R. P., Page, M. G. P., Schalk, I. J., Ceccarelli, M. & Naismith, J. H., 14 Aug 2019, (E-pub ahead of print) In: Nature Communications. 10, 14 p., 3673.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Datasets
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5JQG An apo tubulin-RB-TTL complex structure used for side-by-side comparison
Wang, Y. (Creator), Naismith, J. H. (Creator) & Zhu, X. (Creator), Protein Data Bank (PDB), 18 May 2016
DOI: 10.2210/pdb5JQG/pdb, https://www.rcsb.org/structure/5JQG
Dataset
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5FNV a new complex structure of tubulin with an alpha-beta unsaturated lactone
Wang, Y. (Creator), Naismith, J. H. (Creator) & Zhu, X. (Creator), Protein Data Bank (PDB), 18 May 2016
DOI: 10.2210/pdb5FNV/pdb, https://www.rcsb.org/structure/5FNV
Dataset
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A periplasmic depolymerase provides new insight into ABC transporter-dependent secretion of bacterial capsular polysaccharides (PDB entry 6FI2)
Naismith, J. H. (Creator), McMahon, S. A. (Creator), Le Bas, A. (Creator), Liston, S. D. (Creator) & Whitfield, C. (Creator), Protein Data Bank (PDB), 22 May 2018
DOI: 10.2210/pdb6FI2/pdb, https://www.rcsb.org/structure/6FI2
Dataset