Posttranslational control of our innate immune response: exploring a novel role for ISGylation

Project: Standard

ISG15-dependent stabilisation of USP18 is necessary but not sufficient to regulate type I interferon signalling in humans
Vasou, A., Nightingale, K., Cetkovská , V., Scheler, J., Bamford, C. G. G., Andrejeva, J., Rowe, J. C., Swatek, K. N., Schwarz-Linek, U., Randall, R. E., McLauchlan, J., Weekes, M. P., Bogunovic, D. & Hughes, D. J., 11 Feb 2025, In: European Journal of Immunology. 55, 2, 16 p., e202451651.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Highly sensitive reporter cell line for detection of interferon types I–III and their neutralization by antibodies
Groen, K., Kuratli, R., Sar, L., Vasou, A., Huber, M., Hughes, D. J. & Hale, B. G., 4 Oct 2024, (E-pub ahead of print) In: European Journal of Immunology. Early View, 4 p., 2451325.
Research output: Contribution to journal › Article › peer-review

Open Access
File
A co-opted ISG15-USP18 binding mechanism normally reserved for deISGylation controls type I IFN signalling
Vasou, A., Nightingale, K., Cetkovska, V., Bamford, C., Andrejeva, J., Randall, R. E., McLauchlan, J., Weekes, M. & Hughes, D. J., 3 Jun 2021, bioRxiv, 38 p.
Research output: Working paper › Preprint

Invited Talk - University of Edinburgh
Hughes, D. J. (Invited speaker)
11 Nov 2019
Activity: Talk or presentation types › Invited talk
Invited Talk - University of Dundee
Hughes, D. J. (Invited speaker)
4 Oct 2019
Activity: Talk or presentation types › Invited talk
Microbiology Society Annual Conference 2019
Hughes, D. J. (Speaker) & Vasou, A. (Speaker)
8 Apr 2019 → 11 Apr 2019
Activity: Talk or presentation types › Presentation

Project Details