Research output per year
Research output per year
Project Details
| Acronym | Natural Product Drug Discovery |
|---|---|
| Status | Finished |
| Effective start/end date | 1/03/13 → 30/11/18 |
Funding
- Leverhulme Trust: £959,121.00
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Fingerprint
Explore the research topics touched on by this project. These labels are generated based on the underlying awards/grants. Together they form a unique fingerprint.
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Structure‐based design, synthesis and biological evaluation of bis‐tetrahydropyran furan acetogenin mimics targeting the trypanosomatid F1 component of ATP synthase
Zacharova, M., Tulloch, L., Gould, E., Fraser, A., King, E., Menzies, S., Smith, T. K. & Florence, G. J., 1 Sept 2019, In: European Journal of Organic Chemistry. 2019, 31-32, p. 5434-5440 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Catalytic and anticatalytic snapshots of a short-form ATP phosphoribosyltransferase
Alphey, M. S., Fisher, G., Ge, Y., Gould, E. R., Guerreiro Machado, T. F., Liu, H., Florence, G. J., Naismith, J. H. & da Silva, R. G., 1 Jun 2018, In: ACS Catalysis. 8, 6, p. 5601-5610 10 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Design and synthesis of broad spectrum trypanosomatid selective inhibitors
Fraser, A. L., Menzies, S. K., King, E. F. B., Tulloch, L., Gould, E. R., Zacharova, M., Smith, T. K. & Florence, G. J., 13 Apr 2018, In: ACS Infectious Diseases. 4, 4, p. 560-567 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Datasets
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Data underpinning- Development of simplified heterocyclic acetogenin analogues as potent and selective Trypanosoma brucei inhibitors
Gould, E. R. (Creator), Morris, J. C. (Creator), Thomson, M. (Creator) & Florence, G. J. (Owner), University of St Andrews, 2016
DOI: 10.17630/720297ce-cab1-437e-aeba-9aa0ace4cb3a
Dataset
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Data Underpinning Simplifying Nature Towards The Design of Broad Spectrum Kinetoplastid Inhibitors Inspired by Acetogenins
Gould, E. R. (Creator), Florence, G. J. (Supervisor), Smith, T. K. (Creator), King, E. F. B. (Creator), Zacharova, M. K. (Creator), Fraser, A. L. (Creator), Menzies, S. K. (Creator) & Tulloch, L. (Creator), University of St Andrews, 6 Mar 2017
DOI: 10.17630/1dd8b881-17c2-48e4-a72f-53af938f4537
Dataset
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Data underpinning: Structure‐based design, synthesis and biological evaluation of bis‐tetrahydropyran furan acetogenin mimics targeting the trypanosomatid F1 component of ATP synthase
Zacharova, M. K. (Creator), Tulloch, L. (Creator), Gould, E. R. (Creator), Fraser, A. L. (Creator), King, E. F. B. (Creator), Menzies, S. K. (Creator), Smith, T. K. (Creator) & Florence, G. J. (Creator), University of St Andrews, 31 May 2019
DOI: 10.17630/e721e294-105c-4a0c-9347-be4e99324249
Dataset
File