Project Details
| Acronym | lipid catabolism |
|---|---|
| Status | Finished |
| Effective start/end date | 1/06/15 → 31/01/19 |
Funding
- Medical Research Council: £651,053.16
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 13 Climate Action
Fingerprint
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Revisiting the dipeptidyl carboxypeptidase inhibitor captopril as a source of pan anti-trypanosomatid agents
Garsi, J. B., Hocine, S., Hensienne, R., Moitessier, M., Denton, H., Major, L. L., Smith, T. K. & Hanessian, S., 15 Sept 2024, In: Bioorganic and Medicinal Chemistry Letters. 110, 12 p., 129883.Research output: Contribution to journal › Article › peer-review
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Antileishmanial chemotherapy through clemastine fumarate mediated inhibition of the Leishmania inositol phosphorylceramide synthase
Mina, J. G. M., Charlton, R. L., Alpizar-Sosa, E., Escrivani, D. O., Brown, C., Alqaisi, A., Borsodi, M. P. G., Figueiredo, C. P., De Lima, E. V., Dickie, E. A., Wei, W., Coutinho-Silva, R., Merritt, A., Smith, T. K., Barrett, M. P., Rossi-Bergmann, B., Denny, P. W. & Steel, P. G., 8 Jan 2021, In: ACS Infectious Diseases. 7, 1, p. 47-63 17 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Oligopeptide signaling through TbGPR89 drives trypanosome quorum sensing
Rojas, F., Silvester, E., Young, J., Milne, R., Tettey, M., Houston, D. R., Walkinshaw, M. D., Pérez-Pi, I., Auer, M., Denton, H., Smith, T. K., Thompson, J. & Matthews, K. R., 10 Jan 2019, In: Cell. 176, 1-2, p. 306-317 12 p., e16.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Datasets
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Structure-based design of a eukaryote-selective antiprotozoal fluorinated aminoglycoside (crystal structure data)
Kanazawa, H. (Creator), Saavedra, O. M. (Creator), Maianti, J. P. (Creator), Young, S. A. (Creator), Izquierdo, L. (Creator), Smith, T. K. (Creator), Hanessian, S. (Creator) & Kondo, J. (Creator), Protein Data Bank (PDB), 30 May 2018
http://dx.doi.org/10.2210/pdb5Z1I/pdb and one more link, http://dx.doi.org/10.2210/pdb5Z1H/pdb (show fewer)
Dataset
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Antileishmanial Chemotherapy through Clemastine Fumarate Mediated Inhibition of the Leishmania Inositol Phosphorylceramide Synthase (dataset)
Dickie, E. A. (Creator) & Smith, T. K. (Creator), Figshare, 2021
Dataset