Exploring interactions of polar fluoraliphatic motifs with biomolecules

O'Hagan, David (PI)

School of Chemistry

Project: Standard

Acronym	Exploring interactions of polar
Status	Active
Effective start/end date	1/12/23 → 30/11/26

Funding

EPSRC: £632,665.60

3 Article

A_2A adenosine receptor agonists with last-step enzymatic ¹⁸F-labelling potential (fluorinase) for positron emission tomography (PET)
Charalambous, N., Schleidt, C., Liu, R., Heitman, L. H., Dall'Angelo, S., O'Hagan, D. & Lowe, P. T., 26 Dec 2025, (E-pub ahead of print) In: European Journal of Organic Chemistry. Early View, 8 p., e202501125.
Research output: Contribution to journal › Article › peer-review

Open Access
File
On the nature of improper hydrogen bonding in RCH₂F and RCHF₂ motifs
Piscelli, B. A., Bühl, M., Cormanich, R. A. & O'Hagan, D., 11 Nov 2025, (E-pub ahead of print) In: Angewandte Chemie International Edition. Early View, 15 p., e18500.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Exploring fluorinase substrate tolerance at C-2 of SAM
Lowe, P. T., Lüddecke, I. T. & O'Hagan, D., 17 Nov 2024, In: ChemBioChem. 7 p., e202400861.
Research output: Contribution to journal › Article › peer-review

Open Access
File

On the Nature of Improper Hydrogen Bonding in RCH2F and RCHF2 Motifs (dataset)
Piscelli, B. (Creator), Buehl, M. (Creator), Cormanich, R. (Creator) & O'Hagan, D. (Creator), University of St Andrews, 17 Nov 2025
DOI: 10.17630/2b2156d9-df59-466a-8863-14dd497e3a11
Dataset

File