Project Details
| Acronym | EU KINDRED |
|---|---|
| Status | Finished |
| Effective start/end date | 1/09/13 → 31/08/16 |
Funding
- European Commission Joint Research Centre: £64,077.37
UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This project contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
Fingerprint
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Towards chemical validation of Leishmania infantum ribose 5-phosphate isomerase as a drug target
Dickie, E. A., Ronin, C., Sá, M., Ciesielski, F., Trouche, N., Tavares, J., Santarem, N., Major, L. L., Pemberton, I. K., MacDougall, J., Smith, T. K., Cordeiro-da-Silva, A. & Ciapetti, P., 19 Apr 2021, (E-pub ahead of print) In: Antimicrobial Agents and Chemotherapy. EarlyResearch output: Contribution to journal › Article › peer-review
Open AccessFile -
Biological evaluation and structure activity relationship of 9-methyl-1-phenyl-9H-pyrido[3,4-b]indole derivatives as anti-leishmanial agents
Ashok, P., Chander, S., Smith, T. K., Prakash Singh, R., Nath Jha, P. & Sankaranarayanan, M., Mar 2019, In: Bioorganic Chemistry. 84, p. 98-105Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Structure‐based design, synthesis and biological evaluation of bis‐tetrahydropyran furan acetogenin mimics targeting the trypanosomatid F1 component of ATP synthase
Zacharova, M., Tulloch, L., Gould, E., Fraser, A., King, E., Menzies, S., Smith, T. K. & Florence, G. J., 1 Sept 2019, In: European Journal of Organic Chemistry. 2019, 31-32, p. 5434-5440 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Datasets
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The crystal structure of the Leishmania infantum Silent Information Regulator 2 related protein 1 (dataset)
Ronin, C. (Creator), Mendes Costa, D. (Creator), Tavares, J. (Creator), Faria, J. (Creator), Ciesielski, F. (Creator), Ciapetti, P. (Creator), Smith, T. K. (Creator), MacDougall, J. (Creator), Cordeiro-da-Silva, A. (Creator) & Pemberton, I. K. (Creator), Protein Data Bank (PDB), 28 Feb 2018
DOI: 10.2210/pdb5OL0/pdb, https://www.rcsb.org/structure/5OL0
Dataset
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Different mutations in a P-type ATPase transporter in Leishmania parasites are associated with cross-resistance to two leading drugs by distinct mechanisms (dataset)
Fernandez-Prada, C. (Creator), Vincent, I. M. (Creator), Brotherton, M.-C. (Creator), Roberts, M. (Creator), Roy, G. (Creator), Rivas, L. (Creator), Leprohon, P. (Creator), Smith, T. K. (Creator) & Ouellette, M. (Creator), Figshare, 2016
Dataset
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Data underpinning: Structure‐based design, synthesis and biological evaluation of bis‐tetrahydropyran furan acetogenin mimics targeting the trypanosomatid F1 component of ATP synthase
Zacharova, M. K. (Creator), Tulloch, L. (Creator), Gould, E. R. (Creator), Fraser, A. L. (Creator), King, E. F. B. (Creator), Menzies, S. K. (Creator), Smith, T. K. (Creator) & Florence, G. J. (Creator), University of St Andrews, 31 May 2019
DOI: 10.17630/e721e294-105c-4a0c-9347-be4e99324249
Dataset
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