Dissecting the Molecular Biology of Cyclic Oligoadenylate Signalling

White, Malcolm (PI)
Gloster, Tracey (CoI)

School of Biology

Project: Standard

Acronym	Dissecting Molecular Biology of Cyclic
Status	Finished
Effective start/end date	1/01/20 → 31/12/23

Funding

BBSRC: £723,924.80

10 Article
1 Review article

Cas10 based 7SL-sRNA diagnostic for the detection of active trypanosomiasis
Gruschow, S., Steketee, P. C., Paxton, E., Matthews, K. R., Morrison, L. J., White, M. F. & Grey, F., 17 Mar 2025, In: PLoS Neglected Tropical Diseases. 19, 3, p. 1-17 17 p., e0012937.
Research output: Contribution to journal › Article › peer-review

Open Access
File
CRISPR antiphage defence mediated by the cyclic nucleotide-binding membrane protein Csx23
Grüschow, S., McQuarrie, S., Ackermann, K., McMahon, S., Bode, B., Gloster, T. & White, M., 12 Apr 2024, In: Nucleic Acids Research. 52, 6, p. 2761-2775 15 p., gkae167.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Activation of Csm6 ribonuclease by cyclic nucleotide binding: in an emergency, twist to open
McQuarrie, S., Athukoralage, J. S., McMahon, S. A., Graham, S., Ackermann, K., Bode, B. E., White, M. F. & Gloster, T. M., 27 Oct 2023, In: Nucleic Acids Research. 51, 19, p. 10590-10605 16 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File

Antiviral Type III Crispr signalling via conjugation of STP and AdoMet
Shirran, S. (Creator) & Chi, H. (Creator), Figshare, 2023
DOI: 10.6084/m9.figshare.c.6646859.v1, https://doi.org/10.17630/sta/799
Dataset
Activation of Csm6 ribonuclease by cyclic nucleotide binding: in an emergency, twist to open (EPR dataset)
Ackermann, K. (Creator) & Bode, B. E. (Creator), University of St Andrews, 5 Dec 2023
DOI: 10.17630/dd5a8ddf-4178-4602-8d90-407955431f3f
Dataset

File
Structure of Can2 from Sulfobacillus thermosulfidooxidans in complex with cyclic tetra-adenylate (cA4) (dataset)
McQuarrie, S. J. (Creator), McMahon, S. (Creator), Gloster, T. (Creator), White, M. (Creator), Graham, S. (Creator), Zhu, W. (Creator) & Gruschow, S. (Creator), Protein Data Bank (PDB), 2021
DOI: 10.2210/pdb7bdv/pdb, https://www.rcsb.org/structure/7BDV
Dataset