Research output per year
Research output per year
- 38 results
Search results
-
2022
Scope, limitations and mechanistic analysis of the HyperBTM-catalyzed acylative kinetic resolution of tertiary heterocyclic alcohols
Smith, S., Greenhalgh, M. D., Feoktistova, T., Walden, D. M., Taylor, J. E., Cordes, D. B., Slawin, A. M. Z., Cheong, P.H.-Y. & Smith, A. D., 11 Jan 2022, In: European Journal of Organic Chemistry. p. 30-43 14 p., e202101111.Research output: Contribution to journal › Article › peer-review
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2021
Catalytic enantioselective synthesis of 1,4-dihydropyridines via the addition of C(1)-ammonium enolates to pyridinium salts
McLaughlin, C., Bitai, J., Barber, L., Slawin, A. & Smith, A. D., 6 Aug 2021, (E-pub ahead of print) In: Chemical Science. Advance Article, 11 p.Research output: Contribution to journal › Article › peer-review
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Enantioselective synthesis of α-aryl-β2-amino-esters by cooperative isothiourea and Brønsted acid catalysis
Zhao, F., Shu, C., Young, C. M., Carpenter-Warren, C., Slawin, A. M. Z. & Smith, A. D., 11 May 2021, In: Angewandte Chemie International Edition. 60, 21, p. 11892-11900 10 p.Research output: Contribution to journal › Article › peer-review
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Isothiourea-catalyzed enantioselective α-alkylation of esters via 1,6-conjugate addition to para-quinone methides
Arokianathar, J. N., Hartley, W., McLaughlin, C., Greenhalgh, M. D., Stead, D., Ng, S., Slawin, A. M. Z. & Smith, A. D., 20 Oct 2021, In: Molecules. 26, 21, 13 p., 6333.Research output: Contribution to journal › Article › peer-review
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2020
Exploring the scope of tandem palladium and isothiourea relay catalysis for the synthesis of α-amino acid derivatives
Bitai, J., Slawin, A. M. Z., Cordes, D. B. & Smith, A. D., 25 May 2020, In: Molecules. 25, 10, 13 p., 2463.Research output: Contribution to journal › Article › peer-review
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Isothiourea-catalyzed acylative kinetic resolution of tertiary α-hydroxy esters
Qu, S., Smith, S., Laina-Martin, V., Neyyappadath, R., Greenhalgh, M. D. & Smith, A. D., 14 Sept 2020, In: Angewandte Chemie International Edition. 59, 38, p. 16572-16578 8 p.Research output: Contribution to journal › Article › peer-review
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Isothiourea-catalyzed atropselective acylation of biaryl phenols via sequential desymmetrization/kinetic resolution
Munday, E. S., Grove, M., Feoktistova, T., Brueckner, A. C., Walden, D., Young, C. M., Slawin, A. M. Z., Campbell, A., Cheong, P.H.-Y. & Smith, A. D., 11 Mar 2020, (E-pub ahead of print) In: Angewandte Chemie International Edition. Early ViewResearch output: Contribution to journal › Article › peer-review
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Isothiourea-catalyzed enantioselective synthesis of tetrahydro-α-carbolinones
Liu, H., Slawin, A. M. M. & Smith, A. D., 6 Feb 2020, (E-pub ahead of print) In: Organic Letters. Articles ASAPResearch output: Contribution to journal › Article › peer-review
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Isothiourea-catalyzed functionalization of pyrrolyl- and indolylacetic acid: enantioselective synthesis of dihydropyridinones and one-pot synthesis of pyridinones
Zhang, S., Bacheley, L., Young, C. M., Stark, D. G., O'Riordan, T., Slawin, A. M. Z. & Smith, A. D., Oct 2020, In: Asian Journal of Organic Chemistry. 9, 10, p. 1562-1566 5 p.Research output: Contribution to journal › Article › peer-review
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Isothiourea-catalyzed transfer hydrogenation of α,β-unsaturated para-nitrophenyl esters
Wu, J., Young, C. M. & Smith, A. D., 13 Nov 2020, (E-pub ahead of print) In: Tetrahedron. In press, 131758.Research output: Contribution to journal › Article › peer-review
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Tandem sequential catalytic enantioselective synthesis of highly-functionalised tetrahydroindolizine derivatives
Zhang, S., Greenhalgh, M. D., Slawin, A. M. Z. & Smith, A. D., 12 Mar 2020, (E-pub ahead of print) In: Chemical Science. Advance Article, 8 p.Research output: Contribution to journal › Article › peer-review
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2019
Base-free enantioselective C(1)-ammonium enolate catalysis exploiting aryloxides: a synthetic and mechanistic study
McLaughlin, C., Slawin, A. M. Z. & Smith, A. D., 14 Oct 2019, In: Angewandte Chemie International Edition. 58, 42, p. 15111-15119 9 p.Research output: Contribution to journal › Article › peer-review
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Catalytic enantioselective synthesis of perfluoroalkyl-substituted β-lactones via a concerted asynchronous [2+2] cycloaddition: a synthetic and computational study
Barrios Antunez, D.-J., Greenhalgh, M. D., Brueckner, A. C., Walden, D. M., Elías-Rodríguez, P., Roberts, P., Young, B. G., West, T. H., Slawin, A. M. Z., Cheong, P.H.-Y. & Smith, A. D., 28 Jun 2019, In: Chemical Science. 10, 24, p. 6162-6173 12 p.Research output: Contribution to journal › Article › peer-review
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Evaluating aryl esters as bench-stable C(1)-ammonium enolate precursors in catalytic, enantioselective Michael addition-lactonisations
Young, C. M., Taylor, J. E. & Smith, A. D., 21 May 2019, In: Organic & Biomolecular Chemistry. 17, 19, p. 4747-4752Research output: Contribution to journal › Article › peer-review
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Isothiourea-catalysed enantioselective Michael addition of N-heterocyclic pronucleophiles to α,β-unsaturated aryl esters
Shu, C., Liu, H., Slawin, A., Carpenter-Warren, C. L. & Smith, A. D., 23 Oct 2019, (E-pub ahead of print) In: Chemical Science. Advance Article, 7 p.Research output: Contribution to journal › Article › peer-review
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Isothiourea-catalysed regioselective acylative kinetic resolution of axially chiral biaryl diols
Qu, S., Greenhalgh, M. D. & Smith, A. D., 28 Jan 2019, (E-pub ahead of print) In: Chemistry - A European Journal. Early ViewResearch output: Contribution to journal › Article › peer-review
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Isothiourea-catalysed sequential kinetic resolution of acyclic (±)-1,2-diols
Harrer, S., Greenhalgh, M. D., Neyyappadath, R. M. & Smith, A. D., Aug 2019, In: Synlett. 30, 13, p. 1555-1560Research output: Contribution to journal › Article › peer-review
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NHC-catalysed enantioselectiveintramolecular formal [4+2] cycloadditions using carboxylic acids as azolium enolate precursors
Attaba, N. & Smith, A. D., 6 Dec 2019, (E-pub ahead of print) In: Tetrahedron. In pressResearch output: Contribution to journal › Article › peer-review
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Synthesis of fused indoline-cyclobutanone derivatives via an intramolecular [2+2] cycloaddition
Neyyappadath, R. M., Greenhalgh, M. D., Cordes, D. B., Slawin, A. M. Z. & Smith, A. D., 12 Apr 2019, (E-pub ahead of print) In: European Journal of Organic Chemistry. Early ViewResearch output: Contribution to journal › Article › peer-review
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Unanticipated silyl transfer in enantioselective α,β-unsaturated acyl ammonium catalysis using silyl nitronates
Matviitsuk, A., Greenhalgh, M. D., Taylor, J. E., Nguyen, X. B., Cordes, D. B., Slawin, A. M. Z., Lupton, D. W. & Smith, A. D., 23 Dec 2019, (E-pub ahead of print) In: Organic Letters. Article ASAPResearch output: Contribution to journal › Article › peer-review
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2018
A C=O•••isothiouronium interaction dictates enantiodiscrimination in acylative kinetic resolution of tertiary heterocyclic alcohols
Greenhalgh, M. D., Smith, S. M., Walden, D. M., Taylor, J. E., Brice, Z., Robinson, E. R. T., Fallan, C., Cordes, D. B., Slawin, A. M. Z., Richardson, H. C., Grove, M. A., Cheong, P.H.-Y. & Smith, A. D., 12 Mar 2018, In: Angewandte Chemie International Edition. 57, 12, p. 3200-3206 7 p.Research output: Contribution to journal › Article › peer-review
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Acylative kinetic resolution of alcohols using a recyclable polymer-supported isothiourea catalyst in batch and flow
Neyyappadath, R., Chisholm, R., Greenhalgh, M. D., Rodriguez-Escrich, C., Pericàs, M. A., Hähner, G. & Smith, A. D., 2 Feb 2018, In: ACS Catalysis. 8, 2, p. 1067-1075 9 p.Research output: Contribution to journal › Article › peer-review
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Best practice considerations for using the selectivity factor, s, as a metric for the efficiency of kinetic resolutions
Greenhalgh, M. D., Taylor, J. E. & Smith, A. D., 20 Sept 2018, In: Tetrahedron. 74, 38, p. 5554-5560 7 p.Research output: Contribution to journal › Article › peer-review
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Chiral AuI- and AuIII-isothiourea complexes: synthesis, characterization and application
Gasperini, D., Greenhalgh, M., Imad, R., Siddiqui, S., Malik, A., Arshad, F., Choudhary, M. I., Al-Majid, A., Cordes, D., Slawin, A., Nolan, S. & Smith, A. D., 21 Dec 2018, (E-pub ahead of print) In: Chemistry - A European Journal. Early ViewResearch output: Contribution to journal › Article › peer-review
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Evaluating polymer-supported isothiourea catalysis in industrially-preferable solvents for the acylative kinetic resolution of secondary and tertiary heterocyclic alcohols in batch and flow
Guha, N., Neyya Ppadath, R. M., Greenhalgh, M., Chisholm, R., Smith, S., McEvoy, M., Rodríguez-Escrich, C., Young, C. M., Pericas, M. A., Hähner, G. & Smith, A. D., 24 Aug 2018, (E-pub ahead of print) In: Green Chemistry. In pressResearch output: Contribution to journal › Article › peer-review
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Isothiourea-catalyzed enantioselective addition of 4-nitrophenyl esters to iminium ions
Arokianathar, J. N., Frost, A. B., Slawin, A. M. Z., Stead, D. & Smith, A. D., 2 Feb 2018, In: ACS Catalysis. 8, 2, p. 1153-1160Research output: Contribution to journal › Article › peer-review
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Isothiourea-catalyzed enantioselective functionalization of 2-pyrrolyl acetic acid: two-step synthesis of stereodefined dihydroindolizinones
Zhang, S., Taylor, J. E., Slawin, A. M. Z. & Smith, A. D., 24 Aug 2018, (E-pub ahead of print) In: Organic Letters. In pressResearch output: Contribution to journal › Article › peer-review
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Multiple roles of aryloxide leaving groups in enantioselective annulations employing α,β-unsaturated acyl ammonium catalysis
Greenhalgh, M., Qu, S., Slawin, A. & Smith, A. D., 7 Jun 2018, In: Chemical Science. 9, 21, p. 4909-4918 10 p.Research output: Contribution to journal › Article › peer-review
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Selective and catalytic carbon dioxide and heteroallene activation mediated by cerium N-heterocyclic carbene complexes
Arnold, P. L., Kerr, R. W. F., Weetman, C., Docherty , S. R., Rieb, J., Cruickshank, F. L., Wang, K., Jandl, C., McMullon, M. W., Pöthig, A., Kühn, F. E. & Smith, A. D., 10 Sept 2018, (E-pub ahead of print) In: Chemical Science. Advance Article, 11 p.Research output: Contribution to journal › Article › peer-review
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2017
Aryloxide-facilitated catalyst turnover in enantioselective α,β-unsaturated acyl ammonium catalysis
Matviitsuk, A., Greenhalgh, M., Barrios Antunez, D., Slawin, A. & Smith, A. D., 25 Sept 2017, In: Angewandte Chemie. 129, 40, p. 12450-12455 6 p.Research output: Contribution to journal › Article › peer-review
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Catalytic enantioselective [2,3]-rearrangements of allylic ammonium ylides: a mechanistic and computational study
West, T. H., Walden, D. M., Taylor, J. E., Brueckner, A. C., Johnston, R. C., Cheong, P.H.-Y., Lloyd-Jones, G. C. & Smith, A. D., 29 Mar 2017, In: Journal of the American Chemical Society. 139, 12, p. 4366-4375 10 p.Research output: Contribution to journal › Article › peer-review
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Enantioselective NHC-catalysed redox [4+2]-hetero-Diels-Alder reactions using α-aroyloxyaldehydes and unsaturated ketoesters
Taylor, J. E., Davies, A. T., Douglas, J. J., Churchill, G. & Smith, A. D., 15 Feb 2017, In: Tetrahedron: Asymmetry. 28, 2, p. 355-366Research output: Contribution to journal › Article › peer-review
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Enantioselective N-heterocyclic carbene catalyzed formal [3+2] cycloaddition using α-aroyloxyaldehydes and oxaziridines
Kerr, R. W. F., Greenhalgh, M. D., Slawin, A. M. Z., Arnold, P. L. & Smith, A. D., 15 Jan 2017, In: Tetrahedron: Asymmetry. 28, 1, p. 125-134Research output: Contribution to journal › Article › peer-review
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Enantioselective synthesis of β-fluoro-β-aryl-α-amino pentenamides by organocatalytic [2,3]-sigmatropic rearrangement
Kasten, K., Slawin, A. M. Z. & Smith, A. D., 6 Oct 2017, In: Organic Letters. 19, 19, p. 5182-5185 4 p.Research output: Contribution to journal › Article › peer-review
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Isothiourea-catalysed chemo- and enantioselective [2,3]-sigmatropic rearrangements of N,N-diallyl allylic ammonium ylides
West, T. H., Spoehrle, S. S. M. & Smith, A. D., 20 Jul 2017, In: Tetrahedron. 73, 29, p. 4138-4149 12 p.Research output: Contribution to journal › Article › peer-review
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Tandem palladium and isothiourea relay catalysis: enantioselective synthesis of α-amino acid derivatives via allylic amination and [2,3]-sigmatropic rearrangement
Spoehrle, S. S. M., West, T. H., Taylor, J. E., Slawin, A. M. Z. & Smith, A. D., 30 Aug 2017, In: Journal of the American Chemical Society. 139, 34, p. 11895-11902 8 p.Research output: Contribution to journal › Article › peer-review
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2016
Enantioselective stereodivergent nucleophile-dependent isothiourea-catalysed domino reactions
Matviitsuk, A., Taylor, J. E., Cordes, D. B., Slawin, A. M. Z. & Smith, A. D., 5 Dec 2016, In: Chemistry - A European Journal. 22, 49, p. 17748-17757 10 p.Research output: Contribution to journal › Article › peer-review
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Isothiourea-catalysed enantioselective pyrrolizine synthesis: synthetic and computational studies
Stark, D. G., Williamson, P., Gayner, E. R., Musolino, S. F., Kerr, R. W. F., Taylor, J. E., Slawin, A. M. Z., O'Riordan, T. J. C., Macgregor, S. A. & Smith, A. D., 14 Oct 2016, In: Organic & Biomolecular Chemistry. 14, 38, p. 8957-8965 9 p.Research output: Contribution to journal › Article › peer-review
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