Deciphering non-cell autonomous disease mechanisms in human ALS using inducible pluripotent stem (iPS) cell technology

Miles, Gareth Brian (PI)

School of Psychology and Neuroscience

Project: Studentship

2 Article

2 results

2020
Mutant C9orf72 human iPSC-derived astrocytes cause non-cell autonomous motor neuron pathophysiology
Zhao, C., Devlin, A.-C., Chouhan, A. K., Selvaraj, B., Stavrou, M., Burr, K., Brivio, V., He, X., Mehta, A., Story, D., Shaw, C., Dando, O., Hardingham, G., Miles, G. B. & Chandran, S., 11 Mar 2020, In: Glia. 68, 5, p. 1046-1064 19 p.
Research output: Contribution to journal › Article › peer-review

Open Access
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2015
Human iPSC-derived motoneurons harbouring TARDBP or C9ORF72 ALS mutations are dysfunctional despite maintaining viability
Devlin, A.-C., Burr, K., Borooah, S., Foster, J. D., Cleary, E. M., Geti, I., Vallier, L., Shaw, C. E., Chandran, S. & Miles, G. B., 12 Jan 2015, In: Nature Communications. 6, 12 p., 5999.
Research output: Contribution to journal › Article › peer-review

Open Access
File