Deciphering mechanisms underlying the dysfunction of motoneorons derived from ALS patient iPSCs

Project: Studentship

Project Details

AcronymMNDA Studentship
StatusFinished
Effective start/end date27/09/1526/09/18

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  • Mutant C9orf72 human iPSC-derived astrocytes cause non-cell autonomous motor neuron pathophysiology

    Zhao, C., Devlin, A-C., Chouhan, A. K., Selvaraj, B., Stavrou, M., Burr, K., Brivio, V., He, X., Mehta, A., Story, D., Shaw, C., Dando, O., Hardingham, G., Miles, G. B. & Chandran, S., 11 Mar 2020, In: Glia. 68, 5, p. 1046-1064 19 p.

    Research output: Contribution to journalArticlepeer-review

    Open Access
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    27 Citations (Scopus)
  • C9ORF72 repeat expansion causes vulnerability of motor neurons to Ca2+-permeable AMPA receptor-mediated excitotoxicity

    Thangaraj Selvaraj, B., Livesey, M., Zhao, C., Gregory, J., James, O., Cleary, E., Chouhan, A. K., Gane, A., Perkins, E., Dando, O., Lillico, S., Lee, Y-B., Nishimura, A., Poreci, U., Thankamony, S., Pray, M., Vasistha, N., Magnani, D., Borooah, S., Burr, K., & 12 othersStory, D., McCampbell, A., Shaw, C., Kind, P., Aitman, T. J., Whitelaw, B., Wilmut, I., Smith, C., Miles, G. B., Hardingham, G., Wyllie, D. & Chandran, S., 24 Jan 2018, (E-pub ahead of print) In: Nature Communications. 9, 14 p., 347.

    Research output: Contribution to journalArticlepeer-review

    Open Access
    File
    71 Citations (Scopus)