A biochemical boron tagging strategy for biomolecule visualisation and profiling

Watson, Allan (PI)

School of Chemistry

Project: Fellowship

Acronym	A biochemical boron tagging stategy
Status	Finished
Effective start/end date	1/09/22 → 31/08/24

Funding

Leverhulme Trust: £59,695.00

Giving an enzyme scissors: serotonin derivatives as potent organocatalytic switches for DNA repair enzyme OGG1
Varga, M., Ortis, F., Del Prado, A., Eddershaw, A., Scaletti Hutchinson, E., Hank, E. C., Zhou, K., Rudolfová, N., Dodaro, A., Wiita, E., Almlöf, I., Karsten, S., Mamonov, K., Ahmed, S. H., Bentley, K., Wallner, O., Homan, E. J., Scobie, M., Helleday, T. & Prejanò, M. & 4 others, Stenmark, P., de Vega, M., Watson, A. J. B. & Michel, M., 13 Nov 2025, In: Journal of Medicinal Chemistry. 68, 21, p. 22455-22483 29 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Accessing rare α-heterocyclic aziridines via Brønsted acid-catalyzed Michael addition/annulation: scope, limitations, and mechanism
Hilton, T. A., Leach, A., McKay, A. P. & Watson, A. J. B., 28 Feb 2024, (E-pub ahead of print) In: Chemistry - A European Journal. Early View, 8 p., e202303993.
Research output: Contribution to journal › Article › peer-review

Open Access
File
Compatibility assessment of unactivated internal alkynes in rhodium-catalyzed [2+2+2] cycloadditions
Halford-McGuff, J., McKay, A. & Watson, A. J. B., 28 Mar 2024, In: Synlett. 35, p. 2128-2132 5 p.
Research output: Contribution to journal › Article › peer-review

Open Access
File

Photocatalytic C(sp3)–C(sp2) radical-polar crossover cross-coupling of styrenyl boronic acids (thesis data)
Brals, J. (Creator) & Watson, A. J. B. (Supervisor), University of St Andrews, 30 Oct 2023
DOI: 10.17630/66a59db2-4d79-4457-b019-b99bfa9c0eff, https://doi.org/10.17630/sta/640
Dataset: Thesis dataset

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Dataset underpinning "Direct Chan–Lam amination and etherification of aryl BMIDA reagents"
Watson, A. J. B. (Creator), University of St Andrews, 8 Dec 2022
DOI: 10.17630/f842a14f-2843-4266-aa37-64edc78433b9
Dataset

File
Dataset underpinning "A chemoselective polarity-mismatched photocatalytic C(sp3)–C(sp2) cross-coupling enabled by synergistic boron activation"
Watson, A. J. B. (Creator), University of St Andrews, 14 Sept 2023
DOI: 10.17630/33380f7f-28cd-45b8-b55b-dd6b83651e89
Dataset

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