Research output per year
Research output per year
Personal profile
Research overview
Metabolism and Biomarkers Lab
Our research is dedicated to identifying specific metabolic alterations in cancer to drive biomarker discovery and develop innovative therapeutic strategies. By utilizing LC-MS-based metabolomics, we explore potential biomarkers and therapeutic targets for Hepatocellular Carcinoma, Soft Tissue Sarcoma, and Esophageal Cancer. Our goal is to advance cancer diagnostics and treatment through a deeper understanding of tumor metabolism.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Keywords
- RC0254 Neoplasms. Tumors. Oncology (including Cancer)
- Cancer Metabolism
- LCMS Metabolomics
- Cell Signaling
- Autophagy
- Hepatocellular Carcinoma
- Soft Tissue Sarcoma
- Esophageal Cancer
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Current and Future Cancer Chemoprevention Strategies
Santibanez, J., Villar, V. & Echeverria, C., 19 May 2023. 5 p.Research output: Contribution to conference › Paper › peer-review
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Hepatic glutamine synthetase controls N5-methylglutamine in homeostasis and cancer
Villar, V., Allega, M., Deshmukh, R., Ackermann, T., Nakasone, M., Vande Voorde, J., Drake, T., Oetjen, J., Bloom, A., Nixon, C., Müller, M., May, S., Tan, E., Vereecke, L., Jans, M., Blancke, G., Murphy, D., Huang, D., Lewis, D. & Bird, T. & 4 others, , Mar 2023, In: Nature Chemical Biology. 19, 3, p. 292-304 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile7 Citations (Scopus)15 Downloads (Pure) -
Transforming growth factor-β1 in cancer immunology: opportunities for immunotherapy
Villar, V. H., Subotički, T., Đikić, D., Mitrović-Ajtić, O., Simon, F. & Santibanez, J. F., 25 Apr 2023, Advances in molecular pathology. Simon, F. & Bernabeu, C. (eds.). Cham: Springer, Cham, p. 309-328 20 p. (Advances in experimental medicine and biology; vol. 1408).Research output: Chapter in Book/Report/Conference proceeding › Chapter (peer-reviewed) › peer-review
9 Citations (Scopus) -
Mesenchymal stromal cells cultured in physiological conditions sustain citrate secretion with glutamate anaplerosis
Taurino, G., Deshmukh, R., Villar, V. H., Chiu, M., Shaw, R., Hedley, A., Shokry, E., Sumpton, D., Dander, E., D'Amico, G., Bussolati, O. & Tardito, S., 1 Sept 2022, In: Molecular Metabolism. 63, 10 p., 101532.Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)9 Downloads (Pure) -
The metabolic features of tumor-associated macrophages: opportunities for immunotherapy?
Mojsilovic, S. S., Mojsilovic, S., Villar, V. H. & Santibanez, J. F., 24 Aug 2021, In: Analytical Cellular Pathology. 2021, 12 p., 5523055.Research output: Contribution to journal › Review article › peer-review
Open AccessFile12 Citations (Scopus)9 Downloads (Pure)