Personal profile
Teaching activity
Associate Lecturer in the School of Biology
Research interests
My research and teaching interests are in molecular biology, microbiology and parasitology. I am principally focused on researching Human African Trypanosomiasis, a neglected tropical disease of sub-Saharan Africa.
Research overview
Wellcome Trust-funded research concerning the discovery of novel drug targets in lipid metabolism in Trypanosoma brucei, the causative agent of human African sleeping sickness.
Projects from former institutions
Researching the origin of susceptibility of tsetse flies to Trypanosoma spp., the causative agents of African trypanosomiasis, focussing on the contribution of Sodalis glossinidius, the secondary endosymbiont bacteria of tsetse flies. Collaboration with Professor Sue Welburn (Centre for Infectious Diseases, University of Edinburgh).
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being -
SDG 13 Climate Action -
SDG 14 Life Below Water
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Sterols, free fatty acids, and total fatty acid content in the massive Porites spp. corals cultured under different pCO2 and temperature treatments
von Xylander, N. S. H., Young, S., Cole, C. S., Smith, T. K. & Allison, N., 1 Apr 2023, In: Coral Reefs. 42, p. 551-566 16 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Leishmania dual specificity tyrosine regulated kinase 1 (DYRK1) is required for sustaining Leishmania stationary phase phenotype
Rocha, V. P. C., Dacher, M., Young, S. A., Kolokousi, F., Efstathiou, A., Späth, G. F., Pereira Soares, M. B. & Smirlis, D., 11 Feb 2020, (E-pub ahead of print) In: Molecular Microbiology. Early ViewResearch output: Contribution to journal › Article › peer-review
Open AccessFile -
Dual β-lactam combination therapy for multi-drug resistant Pseudomonas aeruginosa infection: enhanced efficacy in vivo and comparison with monotherapies of penicillin-binding protein inhibition
Siriyong, T., Murray, R. M., Bidgood, L. E., Young, S. A., Wright, F., Parcell, B. J., Voravuthikunchai, S. P. & Coote, P. J., 24 Jun 2019, In: Scientific Reports. 9, 13 p., 9098.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Substrate specificity of the neutral sphingomyelinase from Trypanosoma brucei
Dickie, E. A., Young, S. A. & Smith, T. K., Apr 2019, In: Parasitology. 146, 5, p. 604-616 13 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Screening of the MMV and GSK open access chemical boxes using a viability assay developed against the kinetoplastid Crithidia fasciculata
Kipandula, W., Young, S. A., MacNeill, S. A. & Smith, T. K., Jun 2018, In: Molecular and Biochemical Parasitology. 222, p. 61-69 9 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile
Datasets
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Structure-based design of a eukaryote-selective antiprotozoal fluorinated aminoglycoside (crystal structure data)
Kanazawa, H. (Creator), Saavedra, O. M. (Creator), Maianti, J. P. (Creator), Young, S. A. (Creator), Izquierdo, L. (Creator), Smith, T. K. (Creator), Hanessian, S. (Creator) & Kondo, J. (Creator), Protein Data Bank (PDB), 30 May 2018
http://dx.doi.org/10.2210/pdb5Z1I/pdb and one more link, http://dx.doi.org/10.2210/pdb5Z1H/pdb (show fewer)
Dataset
Activities
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ChemistrySelect (Journal)
Young, S. (Reviewer)
21 Apr 2020Activity: Publication peer-review and editorial work types › Peer review of manuscripts
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ChemMedChem (Journal)
Young, S. (Reviewer)
16 Dec 2019Activity: Publication peer-review and editorial work types › Peer review of manuscripts
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ChemistrySelect (Journal)
Young, S. (Reviewer)
5 Jun 2019Activity: Publication peer-review and editorial work types › Peer review of manuscripts
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PLoS Neglected Tropical Diseases (Journal)
Young, S. (Reviewer)
9 Oct 2017 → 20 Oct 2017Activity: Publication peer-review and editorial work types › Peer review of manuscripts
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External examiner of MSc by Research
Young, S. (External examiner)
11 Sept 2017 → 11 Nov 2017Activity: Examination types › External examination