Research output per year
Research output per year
Dr
KY16 9TF
United Kingdom
United Kingdom
Accepting Postgraduate Research Students
The immune system relies on the ability to detect when cells are virally infected, or potentially tumorigenic, and to specifically eliminate these cells. This is achieved by the actions of Major Histocompatibility Complex (MHC) class I molecules, which bind small peptides from the proteolytic turnover of proteins in the cytoplasm, and present these peptides on the cell surface to T lymphocytes. Detection of viral, or non-self, peptides can stimulate the generation of potent anti-viral cytotoxic T lymphocyte responses.
The research focus of the Powis group is the function of Major Histocompatibility Complex (MHC) class I molecules. These molecules function in the immune system by binding and presenting short peptides, around 9 amino acids in length, to T lymphocytes. By this process the immune system can detect and eliminate virally infected cells, or cells that have become altered in some way, such as tumour cells.
Our current research topics in this area incude:
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Review article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
Research output: Contribution to journal › Article › peer-review
McReynolds, N. (Creator), Cooke, F. G. M. (Creator), Chen, M. (Creator), Powis, S. J. (Creator) & Dholakia, K. (Supervisor), University of St Andrews, 15 Dec 2017
DOI: 10.17630/432f1c03-2e78-4bb3-8396-236a1dca0b50
Dataset
Nylk, J. (Creator), Kristensen, M. V. G. (Creator), Mazilu, M. (Creator), Kubasik-Thayil, A. (Creator), Mitchell, C. A. (Creator), Campbell, E. C. (Creator), Powis, S. J. (Creator), Gunn-Moore, F. J. (Creator) & Dholakia, K. (Creator), University of St Andrews, 2015
DOI: 10.17630/68a91fdb-11f2-4410-8f2e-dd436b016bc7
Dataset
Kronenberg, N. M. (Creator), Liehm, P. (Creator), Steude, A. (Creator), Knipper, J. A. (Creator), Borger, J. G. (Creator), Scarcelli, G. (Creator), Franze, K. (Creator), Powis, S. J. (Creator) & Gather, M. C. (Creator), University of St Andrews, 2017
DOI: 10.17630/881e3a6f-4a9b-456a-83e0-05c350d7c716
Dataset
Fikouras, A. (Creator), Schubert, M. (Creator), Karl, M. (Creator), Kumar, J. D. (Creator), Powis, S. J. (Creator), Di Falco, A. (Creator) & Gather, M. C. (Creator), University of St Andrews, 15 Nov 2018
DOI: 10.17630/998faf40-3b86-466f-af09-288dd106606c
Dataset
Gupta, R. (Creator), Chen, M. (Creator), Malcolm, G. P. A. (Creator), Hempler, N. (Creator), Dholakia, K. (Creator) & Powis, S. J. (Creator), University of St Andrews, 30 Apr 2019
DOI: 10.17630/c3b0856b-3400-4211-9e7c-eacfc7082067
Dataset
Powis, S. J. (PI)
1/05/22 → 31/08/22
Project: Standard
Powis, S. J. (PI)
1/09/20 → 31/08/23
Project: Studentship
Shirran, S. L. (PI), Evans, D. J. (CoI), Gloster, T. (CoI), Guimaraes da Silva, R. (CoI), Melo Czekster, C. (CoI), Powis, S. J. (CoI), Sleeman, J. E. (CoI), Smith, T. K. (CoI), Stewart, A. J. (CoI), Westwood, N. J. (CoI) & White, M. (CoI)
1/07/20 → 30/06/21
Project: Standard
Powis, S. J. (Member of editorial board)
Activity: Publication peer-review and editorial work types › Editor of research journal
Powis, S. J. (External examiner)
Activity: Examination types › External examination
Powis, S. J. (External examiner)
Activity: Examination types › External examination
Powis, S. J. (External examiner)
Activity: Examination types › External examination
Powis, S. J. (External examiner)
Activity: Examination types › External examination