Personal profile
Research overview
I am an MRC research fellow based in the School of Medicine at the University of St Andrews. My research interests lie in developing in host mathematical models for infectious diseases. Also working with the Mathematical Biology group in the School of Mathematics, my research involves using partial and ordinary differential equations, and individual-based models to describe infectious disease spread within the body and to simulate antibiotic treatment strategies. My current multidisciplinary project focuses on developing a spatial model to describe tuberculosis disease progression and treatment in the lungs. Ultimately the model will be capable of simulating new therapeutic approaches for multi-drug resistant tuberculosis.
Profile Keywords
Mathematical modelling; Computational simulation; Infectious diseases; Tuberculosis
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
-
SDG 3 Good Health and Well-being
Fingerprint
- 1 Similar Profiles
Collaborations and top research areas from the last five years
-
Coronal heating and nanoflares: current sheet formation and heating
Bowness, R., Hood, A. W. & Parnell, C. E., Dec 2013, In: Astronomy & Astrophysics. 560, 14 p., A89.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
The relationship between Mycobacterium tuberculosis MGIT time to positivity and cfu in sputum samples demonstrates changing bacterial phenotypes potentially reflecting the impact of chemotherapy on critical sub-populations
Bowness, R., Boeree, M. J., Aarnoutse, R., Dawson, R., Diacon, A., Mangu, C., Heinrich, N., Ntinginya, N. E., Kohlenberg, A., Mtafya, B., Phillips, P. P. J., Rachow, A., Plemper van Balen, G. & Gillespie, S. H., Feb 2015, In: Journal of Antimicrobial Chemotherapy. 70, 2, p. 448-455 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Immune dysregulation in tuberculosis-diabetes comorbidity: mechanistic and translational insights
Saula, A. Y., Cevik, M., Cliff, J. M., Ronacher, K. & Bowness, R., 23 Apr 2026, In: Frontiers in Immunology. 17, p. 1-14 14 p., 1803046.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
A simple label-free method reveals bacterial growth dynamics and antibiotic action in real-time
Hammond, R., Falconer, K., Powell, T., Bowness, R. & Gillespie, S. H., 12 Nov 2022, In: Scientific Reports. 12, 11 p., 19393.Research output: Contribution to journal › Article › peer-review
Open AccessFile -
Modelling the within-host spread of SARS-CoV-2 infection, and the subsequent immune response, using a hybrid, multiscale, individual-based model: Part I: Macrophages
Rowlatt, C. F., Chaplain, M. A. J., Hughes, D. J., Gillespie, S. H., Dockrell, D. H., Johannessen, I. & Bowness, R., 6 May 2022, bioRxiv, 35 p.Research output: Working paper › Preprint
Open Access
Datasets
-
Dataset for the manuscript: Modelling the within-host spread of SARS-CoV-2 infection, and the subsequent immune response, using a hybrid, multiscale, individual-based model. Part I: Macrophages.
Rowlatt, C. F. (Creator), Chaplain, M. A. J. (Creator), Hughes, D. J. (Creator), Gillespie, S. H. (Creator), Dockrell, D. H. (Creator), Johannessen, I. (Creator) & Bowness, R. (Creator), Zenodo, 2022
Dataset
-
Modelling the effects of environmental heterogeneity within the lung on the tuberculosis life-cycle (dataset)
Bowness, R. (Creator), Dobson, S. A. (Creator) & Gillespie, S. H. (Creator), Mendeley Data, 2020
Dataset: Software
Projects
- 3 Finished
-
Using individual-based mathematical: Using individual-based mathematical models to study antibiotic resistance
Bowness, R. (PI)
1/03/18 → 30/09/21
Project: Standard
-
Using CompuCell3D to model tuberculosis: Using CompuCell3D to model tuberculosis growth and treatment
Bowness, R. (PI)
1/05/16 → 30/04/18
Project: Standard
Prizes
-
Member of the RSE Young Academy of Scotland
Bowness, R. (Recipient), 2018
Prize: Election to learned society