Personal profile
Research overview
I am a postdoc in Alan Stewart's group. I am using fluorescence to assess the effect of zinc and other factor on insulin hexamers assembly and disassembly.
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
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SDG 3 Good Health and Well-being
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- 1 Similar Profiles
Collaborations and top research areas from the last five years
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Abnormal plasma/serum magnesium, copper and zinc concentrations associate with the future development of cardiovascular diseases
Lin, B., Alexander, R., Fritzen, R., Mills, S., Stewart, A. J. & McCowan, C., 25 Apr 2025, In: Nutrients. 17, 9, p. 1-14 14 p., 1447.Research output: Contribution to journal › Article › peer-review
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Investigating the conformational landscape of human histidine-rich glycoprotein using amide HDX-MS
Hierons, S. J., Lin, B., Fritzen, R., Blindauer, C. A., Ajjan, R. A., Masson, G. R. & Stewart, A. J., Nov 2025, In: Biochemical Journal. 482, 22, p. 1721-1735 15 p.Research output: Contribution to journal › Article › peer-review
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Properties of the major Zn2+-binding site of human alpha-fetoprotein, a potential foetal plasma zinc carrier
Lu, J., Hierons, S. J., Arya, S., Fritzen, R., Polepalli, S., Khazaipoul, S., Stewart, A. J. & Blindauer, C. A., 4 Feb 2025, In: Chemical Communications. 61, 10, p. 2099-2102 4 p.Research output: Contribution to journal › Article › peer-review
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Targeted removal of the FA2 site on human albumin prevents fatty acid-mediated inhibition of Zn2+-binding
Wu, D., Hierons, S. J., Polepalli, S., Gucwa, M., Fritzen, R., Markiewicz, M., Sabín, J., Minor, W., Murzyn, K., Blindauer, C. A. & Stewart, A. J., 1 Jun 2024, In: Journal of Lipid Research. 65, 6, 12 p., 100560.Research output: Contribution to journal › Article › peer-review
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Magnesium deficiency and cardiometabolic disease
Fritzen, R., Davies, A., Veenhuizen, M., Campbell, M., Pitt, S. J., Ajjan, R. A. & Stewart, A. J., 17 May 2023, In: Nutrients. 15, 10, 19 p., 2355.Research output: Contribution to journal › Review article › peer-review
Open AccessFile
Datasets
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Shedding Light on DNA-Protein Interactions involved in the Nucleotide Excision Repair pathway - Chapter III - SSBs (thesis data)
Fritzen, R. (Creator), Penedo, C. (Supervisor) & White, M. (Supervisor), University of St Andrews, 4 Feb 2023
DOI: 10.17630/963932fc-cc3e-4b69-b92d-58108e138657
Dataset: Thesis dataset
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E-MTAB-10056 - Germinal Center B-Cell gene expression comparison between Wiskott-Aldrich syndrome protein KO mice and WT mice (dataset)
Fritzen, R. (Creator), ArrayExpress – functional genomics data, 2022
https://www.ebi.ac.uk/arrayexpress/experiments/E-MTAB-10056/
Dataset
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Asymmetric base pair opening drives helicase unwinding dynamics (dataset)
Colizzi, F. (Creator), Perez Gonzalez, D. C. (Creator), Fritzen, R. (Creator), Levy, Y. (Creator), White, M. F. (Creator), Penedo-Esteiro, J. C. (Creator) & Bussi, G. (Creator), University of St Andrews, 2019
DOI: 10.17630/84c3a74e-eb89-4b37-a3ed-cd1cf0feeae3
Dataset
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Targeted removal of the FA2 site on human albumin prevents fatty acid-mediated inhibition of Zn2+-binding (dataset)
Wu, D. (Creator), Hierons, S. (Creator), Polepalli, S. (Creator), Gucwa, M. (Creator), Fritzen, R. (Creator), Markiewicz, M. (Creator), Sabín, J. (Creator), Minor, W. (Creator), Murzyn, K. (Creator), Blindauer, C. A. (Creator) & Stewart, A. J. (Creator), University of St Andrews, 23 May 2024
DOI: 10.17630/ae9d50a4-e164-454a-86ee-330d654214b1
Dataset
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Structural and biochemical characterisation of Co2+-binding sites on serum albumins and their interplay with fatty acids (dataset)
Wu, D. (Creator), Gucwa, M. (Creator), Czub, M. P. (Creator), Cooper, D. R. (Creator), Shabalin, I. G. (Creator), Fritzen, R. (Creator), Arya, S. (Creator), Schwarz-Linek, U. (Creator), Blindauer, C. A. (Creator), Minor, W. (Creator) & Stewart, A. J. (Creator), University of St Andrews, 24 May 2023
DOI: 10.17630/34d5ba8e-569d-4630-aac7-8c61a64928a0, https://proteindiffraction.org/search/?q=+8EW4 and 3 more links, https://proteindiffraction.org/search/?q=8EW7, https://proteindiffraction.org/search/?q=8EY5, https://proteindiffraction.org/search/?q=7MBL (show fewer)
Dataset
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Activities
- 2 Peer review of manuscripts
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Frontiers in Molecular Biosciences (Journal)
Fritzen, R. (Member of editorial board)
30 Oct 2025 → 26 Jan 2026Activity: Publication peer-review and editorial work types › Peer review of manuscripts
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Biological Trace Element Research (Journal)
Fritzen, R. (Member of editorial board)
Apr 2024Activity: Publication peer-review and editorial work types › Peer review of manuscripts
Thesis
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Shedding light on DNA-protein interactions involved in the nucleotide excision repair pathway
Fritzen, R. (Author), White, M. F. (Supervisor) & Penedo-Esteiro, J. C. (Supervisor), 30 Nov 2021Student thesis: Doctoral Thesis (PhD)