Rafael Guimaraes da Silva

Search results

• Transition states for psychrophilic and mesophilic (R)-3-hydroxybutyrate dehydrogenase-catalyzed hydride transfer at sub-zero temperatures (dataset)

  Guimaraes da Silva, R. (Creator), UniProt, 2021

  https://www.uniprot.org/uniprot/Q4FRT2 and one more link, https://www.uniprot.org/uniprot/A0A1E3M3N6 (show fewer)

  Dataset

• Allosteric rescue of catalytically impaired ATP phosphoribosyltransferase variants links protein dynamics to active-site electrostatic preorganisation (dataset 2)

  Fisher, G. (Creator), Corbella, M. (Creator), Alphey, M. S. (Creator), Nicholson, J. (Creator), Read, B. (Creator) & Guimaraes da Silva, R. (Creator), Zenodo, 2022

  DOI: 10.5281/zenodo.7077771

  Dataset

• ATP phosphoribosyltransferase (HisZG ATPPRT) from Psychrobacter arcticus (PDB entry 5M8H)

  Stroek, R. (Creator), Ge, Y. (Creator), Talbot, P. D. (Creator), Glok, M. K. (Creator), Bernas, K. E. (Creator), Thomson, C. M. (Creator), Gould, E. R. (Creator), Alphey, M. S. (Creator), Liu, H. (Creator), Florence, G. J. (Creator), Naismith, J. H. (Creator) & Guimaraes da Silva, R. (Creator), Protein Data Bank (PDB), 6 Sept 2017

  DOI: 10.2210/pdb5M8H/pdb, http://dx.doi.org/10.2210/pdb5m8h/pdb

  Dataset

• Dissecting the mechanism of (R)-3-hydroxybutyrate dehydrogenase by kinetic isotope effects, protein crystallography, and computational chemistry (dataset)

  Guerreiro Machado, T. F. (Creator), McMahon, S. (Creator), Read, B. (Creator), Gloster, T. (Creator) & Guimaraes da Silva, R. (Creator), Figshare, 2020

  https://figshare.com/collections/Dissecting_the_Mechanism_of_i_R_i_3-Hydroxybutyrate_Dehydrogenase_by_Kinetic_Isotope_Effects_Protein_Crystallography_and_Computational_Chemistry/5231696

  Dataset

• intact mass measurement raw data

  Shirran, S. (Creator) & Guimaraes da Silva, R. (Creator), Figshare, 2022

  DOI: 10.6084/m9.figshare.19658229.v1

  Dataset

• Human 2'-deoxynucleoside 5'-phosphate N-hydrolase 1: mechanism of 2'-deoxyuridine 5'-monophosphate hydrolysis (dataset)

  Devi, S. (Creator), Carberry, A. E. (Creator), Zickuhr, G. M. (Creator), Dickson, A. (Creator), Harrison, D. J. (Creator) & Guimaraes da Silva, R. (Creator), Protein Data Bank (PDB), 2023

  DOI: 10.2210/pdb8osc/pdb, http://doi.org/10.2210/pdb8os9/pdb

  Dataset

• Read 2024 Mass Specs Raw Data, kinetics raw data, and Sequence Alignments

  Read, B. (Creator), Guimaraes da Silva, R. (Creator) & Mitchell, J. (Creator), Figshare, 2024

  DOI: 10.6084/m9.figshare.24631194.v2

  Dataset

• digest data

  Shirran, S. (Creator) & Guimaraes da Silva, R. (Creator), Figshare, 2022

  DOI: 10.6084/m9.figshare.19658367.v1

  Dataset

• Allosteric rescue of catalytically impaired ATP phosphoribosyltransferase variants links protein dynamics to active-site electrostatic preorganisation (dataset)

  Alphey, M. S. (Creator), Read, B. (Creator) & Guimaraes da Silva, R. (Creator), Protein Data Bank archive (PDB), 2022

  DOI: 10.2210/pdb7Z8U/pdb, https://www.rcsb.org/structure/6FCT and 2 more links, https://www.rcsb.org/structure/6FU2, https://www.rcsb.org/structure/7Z6R (show fewer)

  Dataset

• Structure of Staphylococcus aureus m1A22-tRNA methyltransferase

  Gloster, T. (Creator), Melo Czekster, C. (Creator) & Guimaraes da Silva, R. (Creator), Protein Data Bank (PDB), 2022

  DOI: 10.2210/pdb7o4m/pdb, http://doi.org/10.2210/pdb7O4N/pdb and one more link, http://doi.org/10.2210/pdb7O4O/pdb (show fewer)

  Dataset

• Discovery of trifluoromethyl glycol carbamates as potent and selective covalent monoacylglycerol lipase (MAGL) inhibitors for treatment of neuroinflammation (PDB entry 6BQ0)

  McAllister, L. (Creator), Butler, C. (Creator), Mente, S. (Creator), O'Neil (Steven Neil), S. V. (Creator), Fonseca, K. (Creator), Piro, J. (Creator), Cianfrogna, J. (Creator), Foley, T. (Creator), Gilbert, A. (Creator), Harris, A. (Creator), Helal, C. J. (Creator), Johnson, D. S. (Creator), Montgomery, J. I. (Creator), Nason, D. M. (Creator), Noell, S. (Creator), Pandit, J. (Creator), Rogers, B. N. (Creator), Samad, T. A. (Creator), Shaffer, C. L. (Creator), Guimaraes da Silva, R. (Creator), Uccello, D. P. (Creator), Webb, D. (Creator) & Brodney, M. A. (Creator), Protein Data Bank (PDB), 14 Mar 2018

  DOI: 10.2210/pdb6BQ0/pdb, https://www.rcsb.org/structure/6BQ0

  Dataset

• Mapping the structural path for allosteric inhibition of a short-form ATP phosphoribosyltransferase by histidine (dataset)

  Alphey, M. S. (Creator) & Guimaraes da Silva, R. (Creator), Protein Data Bank (PDB), 2 Sept 2019

  DOI: 10.1021/acs.biochem.9b00282

  Dataset